Celiac blood test questions
 

Hi
i have received following blood tests back. next is to do biopsy. what are the chances (%) I have celiac? Any other diseases may contribute to these results?

Anti tTransglutaminase, IgA 5 0-19 U
Anti tTransglutaminase, IgA IgA anti-tTG reference range:
Anti tTransglutaminase, IgA [<20 U negative]
Anti tTransglutaminase, IgA [20-30 U low positive]
Anti tTransglutaminase, IgA [>30 U positive]
Anti tTrasglutaminase, IgG Low Positive

Interesting--
 

--that the anti-tranglutaminase is low positive.

The IgA anti-tranglutaminase test is somewhat correlated with degree of villous damage, so it's likely that unless you get a very expereinced pathologist, they willnot notice extensive atrophy on biopsy.

But that does not mean you do not have celiac, or a wider gluten sensitivity.

Did they do the anti-gliadin IgA and IgG tests? these are less specific to celiac, but often people with gluten sensitivity show isolated elevations in these, often without gastric symptoms (yet), but often with other neurologic or autoimmune symptoms.

Yes, some people are only positive on one test and it looks like the the IgG version maybe is weak positive but you have not posted any number. Also, they did not run the antigliadin tests. Some are ony positive on the antigliadin tests.
Here in this country they are phasing out the antigliadin tests. (because they are only looking for definite end-stage celiac)

nora

More test results
 

Here are more test results the GI took:

ERYTHROCYTE SEDIMENTATION RATE 3 0-20 mm/hr
CRP, high sensitivity 0.2 0.0-10.0 mg/L
IMMUNOGLOBULIN A 238 65-420 mg/dL
Anti Endomysial, IgA Negative NEG-

I will have to ask what the exact values are of the 'negative' tests.

can anyone read my celiac blood test:
IGA (serum) 249,
cerevisiae AB IGA 25.1,
cerevisiae AB IGA 50.6

Well--
 

--it loks like your total IgA is in "normal" ranges, but the other two tests, did they come with reference ranges?

Help with reading blood test
 

Do you think you can read this blood test?

The test says:

S. cerevisiae AB (IGG)
S. cerevisiae AB ASCA IgG 25.1

(Reference range is 20.1-29.9 is equivocal)
(<=20 negative & >=30 positive)

S. cerevisiae AB (IGA)
S. cerevisiae AB ASCA IgA 50.6

(Reference Range>25.0 Positive)
(<20.0= negative & >25.0 Positive)

IGA Serum 249
(Reference Range <7 negative & >10 Positive)

Well, it does look as if you are positive for--
 

--Anti-Saccharomyces cerevisiae antibodies (these react to yeast proteins), which are often ordered for those with intestinal symptoms. Measuring these is a sort of indirect way to check for celliac, on the theory that intestinal yeat overabundance is likely in malabsorptive diseases. The antibodies can can be found in almost any autoimmune intestinal condition, from celiac/gluten sensitivity to Crohn's.

so by looking at this do you think its celiac or crohns? I have been extremly tired, i cant eat because everything i get makes me sick :(

Probably no one can make a specific diagnosis--
 

--just from this blood work.

The gold standard for celiac is still an intestinal biopsy that shows flattened villi, which is different from the type of inflammatory infiltration usually found in Crohn's, but there are plenty of people who have both. Moreover, there are people with negative blood work who show up with flattened villi, people with positive blood work who don't--they may have a form of gluten sensitivity that involves primary symptoms that are neuromuscular in nature, rather than gastric--or, the villous samples may be on the way to damage, but not show it unequivocally yet . . .

In any case, it won't hurt to try to eliminate certain classes of foods to see if it helps your symptoms. Generally one tries to eliminate one class of foods each week to see what effect that has. One can conversly eliminate practically everything--basically go on an applesauce, white rice and broth diet--and then add foods back in to see what causes reactions.

The key here is that no one needs a physician's imprimatur to alter diet.