New PN Drugs in the Wings?
 

Hey....anyone have any idea on this? I can ask my neurologist at Weil/Cornell:

http://health.taragana.net/articles/...ral-neuropathy

I would volunteer to be the guinea pig...since the 70's were a humdinger for me, how bad could this stuff be!??

Anyone know anything about it? There is also a phase II from a VC funded pharma that is promising....it is AL (and a number after it)...at any rate...phase II means it is years away.

There is a lot of coin to be made if someone/some entity discovers the path for nerve regen. They can do it in small animals, but alas, the nerves are too long in humans.

Hang in there everyone, and happy and healthy 2009.

Mark

our FDA
 

refused to pass this drug in the US in 2001.
There are no papers on reboxetine regenerating nerves on PubMed.
http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

It has alot of side effects.

But it is available in Europe and Canada.

The claim for nerve regen? I don't know. SSRIs here
actually kill neurons, and cause some new ones to grow in the CNS. But I don't think that function is active in the periphery.

It is a nor-epi reuptake inhibitor and similar to some actions of
Effexor and Cymbalta.

Seems to me that there is confusion, in the first link, between mitigating the symptom of neurpoathic pain, which the new drug may well do, and "curing" the underlying condition of nerve malfunction, which we know has many different causes.

Well, I can tell you even if it is close to Effexor it sure didn't help me. Effexor that is. It made my symptoms worse. Especially the RLS portion of them...

However, I'd love to find something right about now that would work a bit better than what I'm doing ATM. Which is not sleeping cause it's one of "those" nights. Had to get up and take a Mirapex and another half a Tramadol. I should be able to sleep in about 30 minutes unless of course the Mirapex and Tramadol decide to fight it out which means I won't sleep tonight no matter what I do. Whoo hoo considering I have to get up in about 4 hours. Ain't life grand? :o