NeuroTalk Support Groups

NeuroTalk Support Groups (https://www.neurotalk.org/)
-   Parkinson's Disease (https://www.neurotalk.org/parkinson-s-disease/)
-   -   Vitamin D and the immune system: (https://www.neurotalk.org/parkinson-s-disease/68783-vitamin-immune-system.html)

lou_lou 01-08-2009 09:19 AM

Vitamin D and the immune system:
 
Vitamin D and the immune system: role in protection against bacterial infection.
http://tinyurl.com/6uf5tr

Bikle DD.
Veterans Affairs Medical Center, San Francisco, California 94121, USA. Daniel.bikle@ucsf.edu

PURPOSE OF REVIEW: The role of vitamin D extends well beyond that of regulating calcium homeostasis. One of these areas is immune function. Immunity is both adaptive and innate, and vitamin D signaling is operative in both. This review will examine these actions of vitamin D, in particular the role of vitamin D in host defense against infection. RECENT FINDINGS: This review will consider two examples of vitamin D-regulated innate immunity that have been recently explored: the role of vitamin D signaling within macrophages to enable them to respond to and kill Mycobacterium tuberculosis organisms, and the role of vitamin D signaling in the keratinocytes of the epidermis to enable them to respond to disruption of their barrier function. Potential application to periodontal disease will then be considered. SUMMARY: Both adaptive and innate immune processes are two edged: beneficial and harmful. Although suppression of adaptive immunity may be beneficial in a number of self-destructive diseases, such suppression may predispose to infection. Enhancement of innate immunity is clearly beneficial in diseases like tuberculosis, but potentiation of proinflammatory processes can increase tissue destruction as in bone loss in periodontal disease. The balance, however, favors adequate vitamin D nutrition in host defense against infection.

PMID: 18660668 [PubMed - indexed for MEDLINE]

Related ArticlesReview The noncalciotropic actions of vitamin D: recent clinical developments. [Curr Opin Nephrol Hypertens. 2008]

ReviewVitamin D in defense of the human immune response. [Ann N Y Acad Sci. 2007] ReviewVitamin D and innate immunity. [Curr Opin Investig Drugs. 2008]

ReviewVitamin d and its role in cancer and immunity: a prescription for sunlight. [Nutr Clin Pract. 2007]

ReviewThe complex role of vitamin D in autoimmune diseases. [Scand J Immunol. 2008] » See Reviews... | » See All...


http://tinyurl.com/6uf5tr

Lara 01-09-2009 07:13 AM

May have been posted here before, but adding on to the subject...

Archives of Neurology - Prevalence of Vitamin D Insufficiency in Patients With Parkinson Disease and Alzheimer Disease
Archives of Neurology - Vol. 65 No. 10, October 2008

EDITED to add: I really like to real the full text before suggesting an article, but unfortunately at this time I am unable to get that. I can only get the abstract, but it caught my eye. *eye *eye


All times are GMT -5. The time now is 09:05 AM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.