NeuroTalk Support Groups - Has anyone tried Celadrin?

Quote:

* Celadrin® is comprised of innovative, targeted & proprietary cetylated fatty acid esters & other active synergists.
* Celadrin's proprietary compound is scientifically designed to be absorbed rapidly and provide immediate and continuous/cumulative pain relief.
* Celadrin®, available for either oral or topical applications, enhances cell membranes throughout the body and restores fluids that cushion bones and joints to promote flexibility and mobility without pain.
* Celadrin® has been shown to be very safe & efficacious as evidenced by gold standard, double-blind, placebo-controlled clinical & scientific studies.
* Celadrin® is FDA compliant and non prescriptive.

From another website:

Quote:

Celadrin is a blend of eight cetylated fatty acids including myristoleic acid (or cetyl myristoleate), Myristic acid and oleic acid. Studies suggest that these fatty acids, especially myristoleaic acid, help support overall joint health and flexiblility. Celadrin plays a positive role in supporting joing mobility by lubricating cell membranes and affected joints, thereby stopping inflammation and preventing stiffness. There have been no reported side effects in any study to date on Celadrin.

What is an ester?

Quote:

ester (ES-ter)

A type of chemical substance that is a combination of acid and alcohol. Esters are found in essential oils (scented liquid taken from plants).

Here is an excellent article about it by Marcia Zimmerman who is very respected in her field:
http://www.thenutritionsolution.com/cm.htm

Quote:

Cetyl myristoleate is the cetyl alcohol ester of myristoleic acid. Technically, myristoleic acid is known as 9-cis-tetradecenoic acid or by its molecular name, C14 H26 O2, a 14-carbon mono-unsaturated omega-5 fatty acid. Myristoleic acid has undetermined biological significance in humans. It's a natural component of the fat of whales, beavers and bovines and its acetylated form, cetyl myristoleate, is found in a particular species of lab mouse. It's therefore surprising that CM became a potential palliative for arthritis and other rheumatic conditions. Current use of this remarkable material stems from a serendipitous event that occurred in the early 1960's at the US National Institutes of Health (NIH)......Cetyl myristoleate appears to be a safe supplement and well tolerated by most patients, although there is no published information available on its absorption and metabolism. The digestability of CM has been questioned, since some patients fail to respond and a few have reported digestive disturbances, Consequently, physicians may have advised taking high-lipase digestive enzymes to improve utilization. On the flip side is concern that hydrolysis of CM into cetyl alcohol and fatty acids in the gut might reduce its effectiveness.

The bolded sentence indicates why topical forms are now becoming more
common. Please read all of Marcia Zimmerman's article.

The bottom line is that CMO is not showing harmful potential, however, response to it may not be worth the cost. It is a shame that I had to dig around to find the "truth" for you... slick websites like the Celadrin one are only there to SELL, not really inform.

The reason that the Celadrin (CMO) is listed as an inert ingredient, is that there are no definitive studies to show effectiveness for the FDA (which requires effectiveness for labeling). For example, SAMe has 3 categories approved for effectiveness which is very unusual in a supplement. (that is why I use it and I can testify that it works).

A similar thing happens with Biofreeze. It has Ilex in it..which is a very good healing herb. It is the same Ilex that is in Yerba Mate tea.
But it is listed on the ingredients, as inert. I really like Biofreeze. Have you tried it?