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-   -   Clofazimine (https://www.neurotalk.org/multiple-sclerosis/76158-clofazimine.html)

4boysmom 02-02-2009 05:57 PM

Clofazimine
 
Does anyone know anything about this antibiotic for leprosy? I saw this article online today, and it sounds interesting.

Here is a link to the article: http://www.medicalnewstoday.com/articles/137377.php

Twinkletoes 02-02-2009 06:22 PM

Quote:

Originally Posted by 4boysmom (Post 458853)
Does anyone know anything about this antibiotic for leprosy? I saw this article online today, and it sounds interesting.

Here is a link to the article: http://www.medicalnewstoday.com/articles/137377.php

No, I haven't heard anything about it. But it sure sounds interesting!

lady_express_44 02-02-2009 06:42 PM

Well at least we won't turn orange ...

"Clofazimine produces pink to brownish skin pigmentation in 75-100% of patients within a few weeks, as well as similar discoloration of most bodily fluids and secretions. These discolorations are reversible but may take months to years to disappear. The prescribing information indicates that several patients have developed depression as a result of this chronic skin discoloration, resulting in two suicides.

Cases of icthyosis and skin dryness are also reported in response to this drug (8%-28%), as well as rash and pruritis (1-5%).

40-50% of patients develop gastrointestial intolerance. Rarely, patients have died from bowel obstructions and intestinal bleeding, or required abdominal surgery to correct the same."

http://en.wikipedia.org/wiki/Clofazimine

Give it to PwMS . . . they'll try anything! :)

Cherie


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