NeuroTalk Support Groups - New treatment for Barrett's Esophagus

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New treatment for Barrett's Esophagus

i removed this post because i dont have a direct link.

could you please provide the link to this article and then edit out the direct copy paste as right at the bottom is the (c) which means it is copyright violation topost it here in its entirety

thanks

where did you find it, maybe one of the other posters/mods could help with a link?

maybe this?

http://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum

Quote:

Gastrointest Endosc. 2005 Dec;62(6):842-8.Click here to read Links

Comment in:
Gastrointest Endosc. 2005 Dec;62(6):849-52.

Cryoablation of Barrett's esophagus: a pilot study.
Johnston MH, Eastone JA, Horwhat JD, Cartledge J, Mathews JS, Foggy JR.

Gastroenterology, GI Clinic, National Naval Medical Center, 8901 Wisconsin Ave, Bethesda, MD 20889, USA.

BACKGROUND: Numerous ablative modalities have demonstrated varying degrees of efficacy in the eradication of Barrett's esophagus (BE). However, they are associated with either high cost, patient discomfort, complications, tedious application, residual underlying BE, or some combination of the above. The aim of this study was to evaluate the safety and the efficacy of a new cryogenic device by using liquid nitrogen sprayed through an open tipped cryogenic catheter placed through the accessory channel of an upper endoscope. METHODS: A prospective, single center study was performed on patients with a long-standing history of BE followed in a Barrett's registry. Patients with degrees of dysplasia ranging from none to multifocal high-grade dysplasia were treated. All patients were treated with 40 mg rabeprazole 3 times per day during the treatment period. Elimination of acid reflux was confirmed via 24-hour esophageal pH studies. Cryoablation was applied hemicircumferentially to 4-cm-long segments at monthly intervals, until the entire segment of BE was eliminated. RESULTS: Eleven patients were treated. There was reversal of BE in all patients. In 9 of 11 (78%) patients who completed the protocol, there was complete endoscopic and histologic reversal of BE. There was no subsquamous specialized intestinal metaplasia at the 6-month follow-up. No complications occurred. CONCLUSIONS: Based on preliminary results, low-pressure spray cryoablation of BE under direct endoscopic visualization is safe and easy to perform. Its relative lack of patient discomfort and its simplicity and demonstrated efficacy make it a modality that should be further explored in the ablation of GI mucosal lesions such as BE and perhaps early esophageal cancer.

PMID: 16301023 [PubMed - indexed for MEDLINE]

The moderators here would like to have links with quotes from
other sources. It is something they are asking for from all the
posters on other forums too, not just here on PN.

I always try to do that anyway, but sometimes I forget and don't include them for PubMed. The PubMed articles have a code number at the bottom which if typed in to PubMed's keyword field will bring up the article that way. It is an identification number. But many people don't know that.

The abstracts there are not the whole article, they are excerpts themselves.

i dont have the links , it was passed on to me in that form.

Wasn't it Roxie who had some 'new'

type of surgery for her Barretts Esophogus last spring? I think SHE would be one to best speak to this issue. She's been quiet since then but I'm sure she'd let us know about it all, if she's aware.
Miss you Roxie! - j

I did a quick search for you Joe, and came up with quite a few references to that article.

You might find what you're looking for here. :
http://www.google.com.au/search?hl=e...e+Search&meta=

There was an article in my local newspaper yesterday about Barrett's Oesophagus. It was written by a professor of gastro-enterology and was discussing the merits of leaving helicobacter in situ, and not dosing it with antibiotics as is common practice at present.

Very interesting article.