NeuroTalk Support Groups - MS, Celiac Disease and GF Diet

NEW:
[Sustained clinical remission in a patient with remittent-recurrent multiple sclerosis and celiac disease gluten-free diet for 6 years.]
PMID: 19418302 April 2009

No abstract available yet, but the title probably tells the story.

Quote:

Conclusions The concomitant presence of MS with atypical onset, AH and CD likely represents an unusual chance association in our patient but inflammatory immune-mediated damage of the central nervous system triggered by gluten could not be excluded.
A case of multiple sclerosis with atypical onset associated with autoimmune hepatitis and silent coeliac disease.
PMID: 18379737 Feb 2008

Multiple changes in antibodies against various antigens are found in multiple sclerosis (MS). Results - Highly significant increases compared with controls were found for IgA and IgG antibodies against gliadin and gluten. IgA antibodies against casein were significantly increased. Anti-endomycium and anti-transglutaminase antibodies were negative.
IgA antibodies against gliadin and gluten in multiple sclerosis.
PMID: 15355487 Oct 2004

Two atypical patients with a multiple sclerosis (MS)-like illness and evidence of occult celiac disease (CD) were managed by the authors. This prompted screening of a further 49 unselected MS cases for serologic evidence of CD. IgA anti-endomysial antibody was found in one case (2%). IgG anti-gliadin antibody was found in 12% of patients and 13% of blood donors.
Multiple sclerosis and occult gluten sensitivity.
PMID: 15210909 Jun 2004

Unfortunately the rate of misdiagnosis remains around 5%-10%, indicating that 1 in 20 patients thought to have MS has, instead, a condition resembling MS. Conditions often confused with MS may be inflammatory (systemic lupus erythematosus, Sjogren's syndrome, vasculitis, sarcoidosis, Behcet's disease), infectious (Lyme disease, syphilis, progressive multifocal leukoencephalopathy, HTLV-1 infection, herpes zoster), genetic (lysosomal disorders, adrenoleukodystrophy, mitochondrial disorders, CADASIL), metabolic (vitamin B12 deficiency), neoplastic (CNS lymphoma) and spinal (degenerative and vascular malformations) diseases.
The differential diagnosis of multiple sclerosis: classification and clinical features of relapsing and progressive neurological syndromes.
PMID: 11794488 Nov 2001

Neurological manifestations of gastrointestinal disorders are described, with particular reference to those resembling multiple sclerosis (MS) on clinical or MRI grounds. Patients with celiac disease can present cerebellar ataxia, progressive myoclonic ataxia, myelopathy, or cerebral, brainstem and peripheral nerve involvement. Antigliadin antibodies can be found in subjects with neurological dysfunction of unknown cause, particularly in sporadic cerebellar ataxia ("gluten ataxia").
Neurological manifestations of gastrointestinal disorders, with particular reference to the differential diagnosis of multiple sclerosis.
PMID: 11794474 Nov 2001

http://www.direct-ms.org/bestbet.html

Potential Therapeutic Characteristics of Pre-agricultural Diets in the Prevention and Treatment of Multiple Sclerosis . This presentation is narrated by Dr Loren Cordain of the Colorado State University. Dr Cordain is a world renowned expert on health and the original human diet and is the author of the “Paleo Diet” and “The Paleo Diet for Athletes”. He explains how returning to a diet based on lean meats, seafood, fruits and vegetables can prevent and help treat MS and other diseases such as Rheumatoid Arthritis and Crohn’s Disease.

Nutritional Strategies for Controlling Multiple Sclerosis, This presentation addresses diet and MS. It presents the probable causes of MS and how to effectively control those elements. A review of the protective factors and how to incorporate them into your lifestyle are also covered. (Discussion of Food Proteins begins at slide 27)