Chemical Exposure Key to Rising Death Rates in Diabetes, Alzheimer's disease, and PD
 

Chemical Exposure Key to Rising Death Rates in Diabetes, Other Diseases

By Todd Neale, Staff Writer, MedPage Today
Published: July 06, 2009
Reviewed by Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California, San Francisco and
Dorothy Caputo, MA, RN, BC-ADM, CDE, Nurse Planner
http://en.wikipedia.org/wiki/Nitrosamine

LITTLE FALLS, N.J., July 6 -- Rising mortality rates for diabetes, Alzheimer's disease, and Parkinson's disease in recent decades parallel increased exposure to nitrosamines in the food supply and environment, researchers found.

Nitrosamines, nitrates, and nitrites can induce DNA damage, oxidative stress, cell death, and cancer, and they have been associated with insulin resistance, according to Suzanne de la Monte, MD, MPH, of Brown University and Rhode Island Hospital in Providence, and colleagues.

Insulin resistance is a characteristic of normal aging, as well as of diabetes, Alzheimer's disease, and Parkinson's disease. Rates of these diseases have increased so rapidly in recent decades that genetics likely can't explain what is happening, the researchers said in the July issue of the Journal of Alzheimer's Disease.

"Epidemiological trends support exposure rather than genetic causes of these diseases," they said.


Nitrosamines and Cancer - Last updated November, 2000
Nitrosamines in Food, Body Fluids, and Occupational Exposure

* Fried bacon
* Cured meats
* Beer
* Nonfat dry milk
* Tobacco products
* Gastric juices
* Rubber products
* Rubber manufacturing
* Metal industries
* Pesticide production and use
* Certain cosmetics
* Certain chemical manufacturing

IUPAC/International Union of Pure and Applied Chemistry Compendium of Chemical Terminology - the Gold Book: nitrosamines is
N-Nitroso amines, compounds of the structure R2NNO. Compounds RNHNO are not ordinarily isolable, but they, too, are nitrosamines. The name is a contraction of N-nitrosoamine and, as such, does not require the N locant. See also: nitrosamides

From Wikipedia: Nitrosamines are chemical compounds of the chemical structure R1N(-R2)-N=O, some of which are carcinogenic.

NDMA and Other Nitrosamines - Drinking Water Issues

Nitrite in Meat

Campaign for Safe Cosmetics

Nitrosamines in cosmetic products - risk of skin problems?

Examination of Nonfat Dry Milk for the Presence of Nitrosamines 1

dioxin, formaldehyde, phenol, nitrosamines, sodium lauryl sulfate ...
Her shampoo contains cocamide DEA, which is associated with carcinogenic nitrosamines and sodium lauryl sulfate, a known mutagen. ...

Environmental nitrates linked to Alzheimer’s, Parkinson’s, and diabetes
 

Environmental nitrates linked to Alzheimer’s, Parkinson’s, and diabetes

The Examiner (Philadelphia), July 6, 9:51 PM
By Linda Kincaid, MPH, CIH, San Jose Environmental Health Examiner
http://www.examiner.com/x-5101-San-J...s-and-diabetes

Researchers at Rhode Island Hospital discovered a link between nitrates in the environment and deaths from common diseases. As exposure to environmental and dietary nitrates increased, so did the rates of death from Alzheimer’s, Parkinson’s, and diabetes mellitus.
Suzanne de la Monte, leader of the research team, comments, “We have become the nitrosamine generation”. Nitrates are used as preservatives in food, especially meat products. When combined with the high amine content of meats, nitrosamines are almost always formed. Nitrosamines are also formed easily during high temperature cooking or in the acid environment of the stomach.