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Reflex Sympathetic Dystrophy (RSD and CRPS) Reflex Sympathetic Dystrophy (Complex Regional Pain Syndromes Type I) and Causalgia (Complex Regional Pain Syndromes Type II)(RSD and CRPS)


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did anyone here tried bisphosphonate therapy?

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Old 12-16-2012, 08:51 PM #11
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Hello cjai- Would you be able to forward some of the links related to the following when you get time?
(other studies that show benefit to those with chronic CRPS, although the benefit may not be as pronounced as with those who have had CRPS a shorter time).

My pain is pretty awful today.
Many thanks!
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Old 12-16-2012, 09:53 PM #12
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...And here is one most significant ones I saw for non-acute CRPS patients that fMichael had quoted at the prior link just above:

The reported duration of limb pain was 4.3±3.1 years...

An Open-label Pilot Trial of Ibandronate for Complex Regional Pain Syndrome, Breuer B, Pappagallo M, Ongseng, Chen CI, Goldfarb R, Clin J Pain. 2008;24:685-689
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Old 01-09-2013, 02:35 AM #13
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I bring up this post again to see if there are any others with crps that can respond about their experience with bisphosphonate therapy please? I am trying to decide on this treatment in the next few weeks. Thank you!
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Old 01-11-2013, 09:32 PM #14
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It is postulated osteoclast hyperactivity is the dominant mechanism involved
in localized osteoporosis seen in CRPS.

Strontium a mineral similiar to calcium benefically affects both aspects of
bone remodeling. It not only enhances bone forming activity but slows
down the development of the osteoclasts.
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