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Reflex Sympathetic Dystrophy (RSD and CRPS) Reflex Sympathetic Dystrophy (Complex Regional Pain Syndromes Type I) and Causalgia (Complex Regional Pain Syndromes Type II)(RSD and CRPS) |
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08-25-2010, 03:04 AM | #2 | |||
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Dear Becky -
Congradulations! It sounds as though you are getting top medical care. And in contrast to what you've experienced over the last 8 weeks, a lot of women appear go into remission during pregnancy, but I'm not sure exactly at what point that kicks in. (And for what it's worth, your pre-pregnancy level of activity sounds pretty good for an RSD patient; and I wouldn't be surprised if cutting back on equestrian stuff wasn't asked of most pregnant women in the first place.) This is a topic that been the subject of a number of good threads here over the years. Here are five of them, beginning with the oldest start date: 1. Pregnancy and RSD - 10/03/06 http://neurotalk.psychcentral.com/showthread.php?t=2612The reason I included CRPS and autoimmunity is because it goes to the apparent mechanism of remission, which is (1) there is strong evidence, especially in the first 3 years of RSDS/CRPS that there is a neuro-aotoimmune component, and (2) a number of autoimmunue diseases have been shown to go into remission during pregnancy, where the whole purpose of immune systems is to distinguish "self" from "other" and take out the "other" - something that obviously goes very wrong in autoimmune conditions - but that is really besides the point. The key thing is that during pregnancy, the woman's body can't go around trying to neutralize the "other" she is carrying, and as a result, some immune activity is given a time out for the duration. That it may come back in a big way post-partem is also part and parcel of the same suggested mechanism. In CRPS and autoimmunity there is a citation to a key article that wasn't then available in free full text: Autoimmune disease during pregnancy and the microchimerism legacy of pregnancy, Adams Waldorf KM, Nelson JL, Immunol Invest. 2008; 37(5): 631-44. Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA. adamsk@u.washington.eduhttp://www.ncbi.nlm.nih.gov/pubmed/1...ubmed_RVDocSum A free PubMed Central copy of the entire article is now available at http://www.ncbi.nlm.nih.gov/pmc/arti...ihms116398.pdf I recommend it highly. It has also been recently followed by another freely available article co-authored by one of the study's authors: The hidden maternal-fetal interface: events involving the lymphoid organs in maternal-fetal tolerance, Taglauer ES, Adams Waldorf KM, Petroff MG, Int J Dev Biol. 2010;54(2-3): 421-30, FULL TEXT @ http://www.ijdb.ehu.es/web/paper.php?doi=082800et&a=f Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS, USA.http://www.ncbi.nlm.nih.gov/pubmed/19876825 I hope these threads are useful. Mike |
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"Thanks for this!" says: | finz (08-26-2010) |
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