Have other CRPS members had experience with intranasal ketamine?
I would like to know how well it worked and any information you have on the related risks. Thank you.

I am scheduled for starting this intranasal treatment next week. From what I have read I learned the following: ketamine is a major anti-inflammatory and analgesic. The nasal form is more effective for pain than the oral form. It has shown positive results in neuropathic & nociceptive pain.
Any further input?

Where have you guys gotten this before? Is it FDA approved? I would LOVE to try Intranasal Ketamine! Ketamine is something I have been seriously looking into. Anything to get out of this hell! Any information is appreciated.
Gentle hugs

Dear Nalakity-Not sure if FDA approved. It will be my first time on this medication. This is with Nancy Sajben, San Diego, CA. What have you tried? I hope to hear from others that have tried nasal or oral ketamine.

My daughter takes both internasal or sublingual from Dr Sajben as well. It provides her some relief but she has to be careful to stay fully hydrated so as to avoid bladder/kidney issues.

Thx betsykk!! Does your daughter just take ketamine when bad pain flares or on a schedule routinely to keep pain low?
Is sublingual easier than nasal to use?
I have been up to 6 to 8 sprays trying to figure out my dose and my nostrils were caked with the KET so it would not absorb more well.

My daughter has been in 5 ketamine coma’s. Her MD just admits her to the hospital for pain control and starts giving her the ketamine. Just be forwarned, it doesn’t work for everyone, and it really messes with your brain. Ketamine is a “horse tranquilizer” and is/was used as a general anesthesia med. It disassociates your brain and wipes it clean, hopefully including the pain. But with neuropathic pain (CRPS) the brain is so hardwired to remember that it has a hard time forgetting that. Ketamine is NOT an antiinflammatory and does nothing for the inflammation process. It is strictly a mind altering drug, that is why it is so popular in the night clubs and referred to as “special K”.
My daughter has been effected with RSD in both of her legs hips to toes and been hospitalized 12 times in the last 18 months. We have learned a lot. It is so frustrating for these patients inflicted with RSD, my heart breaks. I hope there is someday a cure for all!!!!!
Please know we cannot continue to suffer in silence and the FDA needs to know that many different things work for different people. There is no one medication that works for everyone. I am a RN and work for a major insurance company I am working on getting insurance companies to look at individual cases and not pay attention to what the FDA says!!! We need to band together.

Are you sure it's coma and not infusions. The Comas last for 5 days where she is completely out and are banned in the US.

I am positive it is a Ketamine coma, she was on a ventilator. I have been a RN for 20+ years and the difference between infusion and coma has to do with dose and duration of medication. She has had the infusions also as an inpatient but the coma’s were high dose and mechanical ventilation. It is so scary having to watch that!!!

Ketamine is FDA-approved in the United States for two-day use when the patient is awake. The comas aren't approved and most likely won't be for a while.