[flora99]

Hi to everone,
Im AB positive blood groupe, which is a bit unuseual,i was wondering if RSD was linked to blood groupe
Or could it be genetic?
Is there any research in this area?

Would be interested to know

Flora99

[Brambledog]

Well....

I'm not sure on the research tbh, but a lot of scientists have admitted that there's very little high quality research being done into CRPS, so it's difficult to know. There are hints at all sorts of links including genetic, but just because it hasn't been properly looked at yet doesn't mean much. I was reading a paper the other day that mentioned that there was some evidence to suggest a genetic link, and a predisposition to developing CRPS in the children of a parent suffering the disease.

My father has neurological problems in his feet (he had surgery as a young man) which have been getting worse with age. He has had nerve conduction studies that showed his nerves are nor working as they should - however, it is not CRPS (he mentioned to his neurologist about me having it), but his doc was interested that both he and I have persistent neuro issues that are resistant to treatment or pain meds, and admitted it might not be a complete coincidence (he'll have to be careful talking loose like that, he could be struck off ).

So yes, if I'm honest I think there's a fair chance of a genetic component that puts us at greater risk of developing it. I have coeliac disease, another auto-immune condition, and that's been proven to be genetic - so one of my parents has it (we're not sure which, probably my dad again lol - he won't be tested). As CRPS seems to be auto-immune as well, maybe there is that link as well...

Oh yes, and I am O-negative, which is rare-ish too.

Anyhow...just my opinions

Bram.

[Brambledog]

http://www.londonpainclinic.com/comp...pain-syndrome/

There is a lot of evidence-based papers and discussion about CRPS on this site. Well worth a few hours of light reading

Bram.

[flora99]

Thats really interesing Brambledog.,that your blood groupe is unusual too!
I wonder if there is a high proportion of people with an unusual blood groupe?
Thankyou for telling me about the link with your father.I didnt know RSD was thought to be an autoimmune thing.
I dont know my fathers full medical history as i was adopted.
Thankyou for your interesting reply.
Big Hug
X

[flora99]

Thankyou i will certainly will have a look .
My physio who origonally spotted what i had knew a lot as he had had a mild case of RSD from having whiplash himself.He passed on a lot of what he knew to me,so i understood more than than most after my diagnosis,but that was 10 years ago,and i hope there is more to learn now,especially from other members,as RSD is diferent for everone.

The only study was done by the dutch.
http://rsds.org/2/library/article_ar...turkenboom.pdf

The 2 besty resources fo collected papers I've found are
http://www.thblack.com/links/RSD/index.html
there is a dutch one cotaining every paper ever published there but can't find the link at the moment

[Allanira]

I'm O Positive. Which is 1 of the most common blood groups.

[Nanc]

Very interesting!

I am also O positive. I come from a large family (number 7 of 8 kids). No one else in my family has gluten problems or rsd related issues. Nothing neurologic, except migraines, and some with a few allergies and arthritis. It appears that I got the bucket load of problems

[Allanira]

I read somewhere not too long ago that adults with it can have children with it. They try to say the parent has munchausen (I think is how its spelled) and is passing it off or making a bigger deal of a childs growing pains. It was in a crps research thing from a conference for children with rsd. Don't ask me how I got there for adult onset lol.

[Brambledog]

Originally Posted by Nanc

Very interesting!

I am also O positive. I come from a large family (number 7 of 8 kids). No one else in my family has gluten problems or rsd related issues. Nothing neurologic, except migraines, and some with a few allergies and arthritis. It appears that I got the bucket load of problems

Lol Nanc, I feel the same!

I personally don't see how blood group can have anything to do with it, but I do think genetics could play a part. Just because you or any member of your family carry a gene, doesn't mean that that gene becomes dominant and you suffer symptoms. The reason that some of us develop a condition because of the gene we carry, and some don't, is the interesting possible research for me.

Bram.