You may be in the twenty percent group who due to genetics will have no response or you may need to double dose. Some take it twice a day. Some take as little as 1mg with relief and some also need to take up to 12 mgs. I had no idea that there were so many variables, until I joined the endorphins FB group. Also, there are many stories of people stopping LDN because they believe it isn't working and afterward they realize there were subtle improvements.

I wish you had luck, because it is so distressing to read that you did not, considering my success.

I was able to dance twice at my daughter's wedding, but I did suffer the entire night and two days afterward with a flare. But these flares from "over doing it" while painful, cannot compare to what I suffered with before LDN. I believe if I had gotten LDN earlier I might have had a full remission.