Here is the article from Sweden.

1: J Biomed Discov Collab. 2007 May 4;2:2. Links
Applied information retrieval and multidisciplinary research: new mechanistic hypotheses in Complex Regional Pain Syndrome.Hettne KM, de Mos M, de Bruijn AG, Weeber M, Boyer S, van Mulligen EM, Cases M, Mestres J, van der Lei J.
Safety Assessment, AstraZeneca R&D Molndal, Sweden. k.hettne@erasmusmc.nl.

ABSTRACT: BACKGROUND: Collaborative efforts of physicians and basic scientists are often necessary in the investigation of complex disorders. Difficulties can arise, however, when large amounts of information need to reviewed. Advanced information retrieval can be beneficial in combining and reviewing data obtained from the various scientific fields. In this paper, a team of investigators with varying backgrounds has applied advanced information retrieval methods, in the form of text mining and entity relationship tools, to review the current literature, with the intention to generate new insights into the molecular mechanisms underlying a complex disorder. As an example of such a disorder the Complex Regional Pain Syndrome (CRPS) was chosen. CRPS is a painful and debilitating syndrome with a complex etiology that is still unraveled for a considerable part, resulting in suboptimal diagnosis and treatment. RESULTS: A text mining based approach combined with a simple network analysis identified Nuclear Factor kappa B (NFkappaB) as a possible central mediator in both the initiation and progression of CRPS. CONCLUSION: The result shows the added value of a multidisciplinary approach combined with information retrieval in hypothesis discovery in biomedical research. The new hypothesis, which was derived in silico, provides a framework for further mechanistic studies into the underlying molecular mechanisms of CRPS and requires evaluation in clinical and epidemiological studies.

PMID: 17480215 [PubMed - in process]

ok, here I go again with another chit chat.
NF-B plays a key role in mediating the survival response of developing neurons to cytokines.
http://www.jcb.org/cgi/content/abstract/148/1/325

I have over a 1500 page pathology book sitting in front of me that is interesting as well. Like most of you this medical stuff is the last thing I want to get involved in.

In my case, I have been told my immune system is ground level. By several MD's so I have done everything I can to build it up. I have been on several antibiotics because in my case something broke the BBB level.

I had a rough eye infection a while back. Eye Doc said Cellulitis, Neuro., Staph, PCP said severe infection one of the worst he seened. Well in my hair dressing opinion I have been invaded with some kind of microorganisms.

cont....

This is going to be long and I am sorry about that. I just don't talk unless I have medical backup. I really don't know anything, I realized that a long time ago. But for those with the DX of Fibro, CFS, Gulf War etc.. Maybe this could help you.
CFS
http://members.aol.com/rgm1/private/nicolson.htm


Chronic Fatigue Syndrome, Fibromyalgia Syndrome and Other Fatigue Conditions

http://www.immed.org/illness/fatigue..._research.html

cont....

All MD's in the States have it very rough. They have got to follow a ABCD order or the AMA will be right on their backs. Like for instance they are not even allowed to tell you a herb could even help. If you don't believe me please ask them.

I have done alot of Alternative Medicine as well. Alternative medication is very complex. Just look at this web site for instance. What has helped me could possiably hurt you, you need someone that knows what they are doing.

http://en.wikipedia.org/wiki/Category:Medicinal_plants

I have sought alternative MD's that know what their doing. They do not believe in the one size fits all approach.

What is getting me better is Conventional and Alternative.

I beg of each and every one of you to be your own advocate. Never ever give up. For every problem their is a solution. Be good to you, Roz

So happy!
 

Roz it makes my heart soar like a hawk to hear you say you are getting better!!!

I am sooo happy for you! Keep us posted as to how your doin cause it gives some of us hope. :winky:

Keep up the good work! :hug: