Hi Biobased

Have you looked into using the prescription 50mg tablets of Naltrexone and disolving it in water and then taking divided liquid doses: eg 1 x 50 mg tablet = 11 x 4.5 mg doses (plus 0.5mg but I wouldn't worry about that extra small amount in solution) Add the tablet to 110mg water (= 11 x 10ml liquid doses). There is lots of information on the LDN sites about measuring and storing. This method would make it very cost effective - and your insurance might cover the prescription.

BTW - I ended up having to stop my LDN trial (re our previous discussion on LDN) - it became obvious that the LDN was suppressing my cortisol levels and as I no longer make any cortisol naturally this was an unsafe risk. I did further research and although there is little academic information on the effect of either Naltrexone or LDN on cortisol levels I did come across several articles where the effect had been observed and tested in clinical situations. This could explain why some people do not do well on LDN - if their adrenal function (ie cortisol production) is already compromised then LDN could make it worse.

I still feel trialing it was worthwhile - how else was I to find out if it might help? I'm pleased that so many are receiving benefit from it and that more research is being done for it's use in specific conditions.

My doctor would not give me the whole pill which was unfortunate, because it is incredibly easy to mix LDN. Easier than mixing a cake mix.

The cheapest supplier is Belmar in CO. A 4.5mg 90 day supply is 49.00 free shipping. Still too high considering I am paying for supplemental drug coverage every month and not using it. I am most likely going to use this provider.

That is very interesting information on LDN and cortisol. I never heard of this, but now that you have posted about it I will investigate. Thank you for posting.

I have been taking LDN for about one month now. I started at 1.5 mg and am now up to 3.0 mg. It has been compounded for me by my local pharmacy with increasing dosages every 7 days of 0.5 mg mixed with Avicel for fast release. So far so good, and I think is a good idea to go slow. My GP is prescribing for me for seven tablets costing me about 17.00 to 18.00 a week. If prescribed for 30 days is less money, so when I get to (hopefully) 4.5 mg will cost a lot less a month. I don't know that I would feel confident mixing this myself with the proper filler.

I think my mood is better now than before I started, pain is a little better around my shoulder (CRPS started after rotator cuff surgery). I don't notice the pain very much during the day, but at night I do especially under my armpit. I also used DMSO 50 percent on my hand for two weeks 1/2 teaspoon twice a day and my hand is now pain free but my fingers are still swollen and somewhat stiff. Before the palm of my hand was very painful. I am able to use my hand because I constantly exercise it. Exercise is terribly important and I am still doing PT six months since surgery. I stopped using DMSO because my hand started burning after application and the tops of my fingers had a flaky look. This cleared up right away after stopping the use of the DMSO.

I wish you luck with your use of LDN.

just wondering does LDN work for both CRPS1 and CRPS 2?

Dr. Chopra states that it does. Treatment of Complex Regional Pain Syndrome (CRPS) Using Low Dose Naltrexone (LDN)

THank you Biobased