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Reflex Sympathetic Dystrophy (RSD and CRPS) Reflex Sympathetic Dystrophy (Complex Regional Pain Syndromes Type I) and Causalgia (Complex Regional Pain Syndromes Type II)(RSD and CRPS)

Promising Clinical Trial Results in Failure

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Old 12-06-2017, 06:18 AM   #1
Join Date: Sep 2011
Posts: 246
Default Promising Clinical Trial Results in Failure

The University of Liverpool's Pain Research Institute at the Institute for Translational Medicine were involved in running a significant clinical trial of low-dose, IV immunoglobulin for treating long-standing CRPS pain. They have just recently announced that the trial of the promising treatment has been a failure. The announcement can be found here:

Promising treatment for Complex Regional Pain Syndrome ineffective - News - University of Liverpool

The announcement also contains a link to the full details of the published randomised clinical trial.
Neurochic is offline   Reply With Quote
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RSD ME (12-11-2017)
Old 12-09-2017, 09:32 AM   #2
Join Date: Jan 2014
Location: NC
Posts: 132

I recently got high dose IVIg - 2g/kg for a total of 125g given at 25g a day over five infusions. This is a pretty high loading dose. I wasn't expecting any relief at all the first dose, especially from the crps, which was actually not the reason I was having it. Surprisingly, I had tremendous pain relief and reduction of edema in my lower right affected quadrant for a few weeks. I'm due to have another infusion at half that amount as soon as insurance gets straightened out.

Maybe they should try high dose in these studies.
cdwall is offline   Reply With Quote
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BioBased (12-18-2017), catra121 (12-09-2017)

announcement, clinical, failure, pain, trial

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