Hi,

You all no I am just a hairdresser, but I came acroos this medication called Piracetam. What are your thoughts on this, wheather good or bad. I am not sensitive in any way shape or form. I really appreciate hearing the neg.- as well. Much Love, Roz xxx

http://www.drugs-pro.com/memory/nootropil.html

.

Hi Roz,


I haven't heard of that drug here but I do know that Alzheimer type medications are prescribed by many Pain Management Doctors now for relief of RSD/CRPS symptoms.
A drug called Memantine is used here, I presume it is similar to Piracetum.
I will certainly do some research for you to find if it is working for anyone in my support group.
Take care
Love Tayla

Oddly, when I go on Medline Plus Drug Info, I can't get a hit for either Piracetam or the brand names it's apparently sold under, Nootropil and Myocalm.

Any help on this one? Is it in fact approved for use in the US?

Mike

Nootropil



Nootropil is known as a Nootropic substance or smart drug, commonly used to improve cognitive functions such as recall, concentration and intelligence. This class of drug has no sedative or psycho stimulating effects, so will not impact the central nervous system. It is recommended for the treatment of attention and memory disorders, and any associated physical manifestations.


How Does Nootropil Work?


The human nervous system deteriorates with age, due in part to the oxidation process. This process destroys brain cells and forms free radicals that cause further damage. Nootropics deactivate free radicals and repair some of the earlier damage by stimulating dormant communication chemicals. They act on the brain by minimizing damage and natural deterioration to brain functions; they repair existing damage, and they enhance a range of cognitive functions to beyond levels that are considered normal. Nootropil targets the Corpus Callosum, the area of the brain that joins the two hemispheres, and allows the user to draw on greater brain potential.


What Is Nootropil Used To Treat?


Nootropil is recommended for the treatment of attention and memory disorders that are associated with age related neurodegenerative illnesses. It has been used to improve alertness, cooperation, socialization and IQ in elderly psychiatric patients suffering from mild diffuse cerebral impairment. Additionally, it has slowed deterioration in senile involution dementia and Alzheimer's disease.


Aside from its more obvious applications, it has been used successfully to treat alcoholism and alcohol withdrawal syndrome in animals and man. Furthermore, it has enhanced reading comprehension, spelling accuracy, and verbal skills in dyslexic children.


Nootropil Liquid has the added benefit of being easy to administer, especially for those who have difficulty swallowing tablets and capsules. It can easily be mixed with either juice or water as desired.

From what I understand Nootropil is a suppyment and cost about $22. for a bottle Of 120 caplets.I have not heard of this supplement and I worked in a health food store for two years, so it may be new or just something we did not carry. But it is sold in the USA I can get the site if you want. Sorry I can't help more.








Piracetam

http://en.wikipedia.org/wiki/Piracetam

Hyperbaric oxygen therapy and piracetam decrease the early extension of deep partial-thickness burns

http://cat.inist.fr/?aModele=afficheN&cpsidt=3197126

I see that Priracetam is also used in the treatment of myclonic jerks here:
http://www.wemove.org/myo/myo_phm.html

and it adds:
Piracetam, which is typically used as an "add-on therapy," is not currently available in the United States.

OOps I just found this:
Its pain relief (analgesic) and fever relief (antipyretic) effects are similar to those of aspirin and it works in a similar, though not identical, way. Unlike aspirin, however, increasing the dose does not result in clinically useful anti-inflammatory activity. Paracetamol is therefore not of value for reducing inflammation in the treatment of chronic rheumatic diseases as are the non-steroidal anti-inflammatory drugs like aspirin. Nevertheless, paracetamol does provide useful pain relief and is considered the first line treatment in osteoarthritis.

found that here:
http://www.pharmweb.net/pwmirror/pwy...rmwebpic1.html

Ok mabie I gotta start taking it, if that link is not the same drug.. now I wonder where I left my computer..

Roz, just where do you come up with some of this stuff? Anyhow, check out this abstact, the link to the free full text article follows:

"Vinpocetine and piracetam exert antinociceptive effect in visceral pain model in mice," Abdel Salam OM, Pharmacol Rep. 2006 Sep-Oct; 58(5): 680-91.

Department of Pharmacology, National Research Centre, Tahrir St., Dokki, Cairo, Egypt. omasalam@hotmail.coml

The effect of vinpocetine or piracetam on thermal and visceral pain was studied in mice. In the hot plate test, vinpocetine (0.9 and 1.8 mg/kg), but not piracetam, produced a reduction in nociceptive response. Vinpocetine (0.45-1.8 mg/kg, ip) or piracetam (75-300 mg/kg, ip) caused dose-dependent inhibition of the abdominal constrictions evoked by ip injection of acetic acid. The effect of vinpocetine or piracetam was markedly potentiated by co-administration of propranolol, guanethidine, atropine, naloxone, yohimbine or prazosin. The marked potentiation of antinociception occurred upon a co-administration of vinpocetine and baclofen (5 or 10 mg/kg). In contrast, piracetam antagonized antinociception caused by the low (5 mg/kg), but not the high (10 mg/kg) dose of baclofen. The antinociception caused by vinpocetine was reduced by sulpiride; while that of piracetam was enhanced by haloperidol or sulpiride. Either vinpocetine or piracetam enhanced antinociception caused by imipramine. The antinociceptive effects of vinpocetine or piracetam were blocked by prior administration of theophylline. Low doses of either vinpocetine or piracetam reduced immobility time in the Porsolt's forced-swimming test. This study indicates that vinpocetine and piracetam possess visceral antinociceptive properties. This effect depends on activation of adenosine receptors. Piracetam in addition inhibits GABA-mediated antinociception.

http://www.if-pan.krakow.pl/pjp/pdf/2006/5_680.pdf

And here's another one, in this case looking at what may be a more potent "piracetam analog" called Nefiracetam:

"Nonopioid and neuropathy-specific analgesic action of the nootropic drug nefiracetam in mice," Rashid MH, Ueda H, J Pharmacol Exp Ther. 2002 Oct;303(1):226-31.

Division of Molecular Pharmacology and Neuroscience, Nagasaki University Graduate School of Biomedical Sciences, Japan.

Nootropic drug nefiracetam and related compounds are used in diseases with learning and memory deficits. Recent studies have implicated relationships between learning, memory, and chronic pain. Thus, in the present report, we have studied the effects of nootropic drug nefiracetam on the thermal and mechanical hyperalgesia induced by partial sciatic nerve ligation or streptozotocin treatment in mice. In the thermal paw withdrawal test, p.o., s.c., i.t., and i.c.v. administration of nefiracetam dose dependently reversed the thermal hyperalgesia observed in nerve-injured mice. Nefiracetam (p.o. and i.t.) also significantly reversed the thermal hyperalgesia observed in streptozotocin-induced diabetic mice. In the paw pressure test, p.o. and i.t. administration of nefiracetam dose dependently reversed the mechanical hyperalgesia observed in both nerve-injured and diabetic mice. In contrast, nefiracetam had no effect in sham-operated or control nondiabetic mice in all paradigms. Among other pyrrolidine nootropics (p.o.), aniracetam produced significant analgesic effects. Other analogs also had some, but not significant, analgesic effects. Finally, nefiracetam (p.o.)-induced analgesia in injured mice was not affected by opioid antagonist naloxone (s.c., i.t., and i.c.v.) but was dose dependently inhibited by nicotinic antagonist mecamylamine (i.t. and i.c.v.). The analgesic effect of i.t. nefiracetam was also blocked by i.t. mecamylamine pretreatment. Together, these findings suggest that nefiracetam, a new member of the piracetam group of cognition enhancers, could be a good therapeutic tool against neuropathic pain. We also demonstrate that nefiracetam-induced analgesic action was nonopioid in nature and was due to stimulation of nicotinic cholinergic system at spinal and supraspinal levels.

http://jpet.aspetjournals.org/cgi/co...full/303/1/226

I would urge folks to open and read both of the articles, the "discussion" portions are fairly interesting.

Mike

Googled list results-
http://www.google.com/search?q=Pirac...ient=firefox-a


from the first page- more pages on the google link above -
Piracetam 800mg. 120 Caps
www.AmericanNutrition.com Premium only $21.95 per bottle Manufactured In The USA
Pure Piracetam 800mg
www.RelentlessImprovement.com Certified Quality, Proven Purity. Same-day shipping from USA.

Piracetam - Wikipedia, the free encyclopedia
Piracetam (brand name: Nootropil®, Myocalm®) is a nootropic. It is a cerebral function regulating drug which, it is claimed, is able to enhance cognition ...
en.wikipedia.org/wiki/Piracetam - 66k - Cached - Similar pages

piracetam research: 114 studies
Piracetam information and research. ... piracetam effect on cerebral metabolism in Alzheimer's. piracetam reverses hippocampal changes in Alzheimer's ...
www.piracetam.com/ - 42k - Cached - Similar pages

CERI: Piracetam Chapter from <i>Smart Drugs & Nutrients
Piracetam is inexpensive (under $0.85 per day) and available by mail (see appendix A). The subjective effect described by some people is that piracetam, ...
www.ceri.com/noot.htm - 11k - Cached - Similar pages

CERI: Smart Drug Update: Piracetam and Altitude
About one year ago, we published an extensive update on piracetam [Vol. 1, No. 10]. In that article, we reported that piracetam was remarkably effective in ...
www.ceri.com/update.htm - 3k - Cached - Similar pages

Piracetam and Down Syndrome
Piracetam is what I refer to as "a drug in search of a disease." A best-selling drug in Europe and Japan, a large portion of sales is to normal adults ...
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Erowid Piracetam (Nootropyl) Vault
Information on Piracetam (Nootropyl) including research, legislation, media coverage, bibliography and lots of links.
www.erowid.org/smarts/piracetam/piracetam.shtml - 13k - Cached - Similar pages

Piracetam - Buy Nootropil
Piracetam (Nootropil) improves brain function and stimulates the central nervous system without any toxicity or addictive properties ...
www.antiaging-systems.com/a2z/piracetam.htm - 18k - Cached - Similar pages

Piracetam ( Nootropil )
Nearly three decades have now passed since the discovery of the piracetam-like nootropics, compounds which exhibit cognition-enhancing properties, ...
www.biopsychiatry.com/piracetam.htm - 5k - Cached - Similar pages

piracetam article by James South
piracetam article and articles on vinpocetine, idebenone, modafinil, deprenyl.
www.smart-drugs.com/ias-piracetam.htm - 102k - Cached - Similar pages

Piracetam therapy does not enhance cognitive functioning in ...
BACKGROUND: Piracetam is widely used as a purported means of improving cognitive function in children with Down syndrome. Its efficacy, however, has not ...
http://www.ncbi.nlm.nih.gov/sites/en...indexed=google - Similar pages

Hi Everyone,

Thanks so much. What do you think about Germanium as well? Much Love, Roz xxx