It would be hard to overstate how valuable I've found this site. It has been both extraordinarily informative and most beneficial pyschologically.

Along those lines, I hope I can hear from anyone who has, in the course of their treatment, undergone Ketamine infusion.

My Pain doctor, who is good and who I trust, wants to do this as our next step. Last week I had my first Stellate Ganglion and Lumbar blocks. I had some, not much, pain relief for a few hours, and then the burning came back, a little stronger actually, in a rebound effect. The burning, by the way, was first present in my abdomen as a result of a surgery and is now spread to my arms, legs, upper back and forehead. My hands and feet, unlike most I have spoken with at support groups, are just fine (if I could just trade in a foot for a new body...)

For medication, I'm at 600 mg Lyrica, along with Tramadol and am now titrating up with Cymbalta, giving me some relief, basically enough to keep from climbing the walls day and night.

My concern with Ketamine are with the side effects. I realize it is for many the best, strongest form of treatment, a 'rebooting' process that works. But, ah, the halluciations (!!)...

You know the person who, when, let's say, a joint was passed around, ended up paranoid on the floor? I'm that guy. Also, I have a minor but present underlying manic condition that is very sensitive to pyschoactive drugs. I'm wondering how beneficial a single, four-hour infusion treatment is that first time. Does one see immediate positive effects (if there are to be any)? My reading on Ketamine led me to believe that it takes a ten day treatment to see improvement, but my doctor (Dr. Josua Prager in LA) said that he pretty much can tell after the first infusion if there are going to be any benefits.

Anyway, I'm in desperate need of relief, but I'm dreading the possibility of four hours of disassociative hallucinations (especially if I'm paying $2000 for such pleasures....)

Thanks to anyone who replies.