Schizophrenia For schizophrenia support.


advertisement
 
 
Thread Tools Display Modes
Old 06-06-2009, 08:02 PM #1
jccgf jccgf is offline
Senior Member (jccglutenfree)
 
Join Date: Aug 2006
Location: Wisconsin
Posts: 1,581
15 yr Member
jccgf jccgf is offline
Senior Member (jccglutenfree)
 
Join Date: Aug 2006
Location: Wisconsin
Posts: 1,581
15 yr Member
Default Gluten Sensitivity and Schizophrenia... yet another look!

Prevalence of Celiac Disease and Gluten Sensitivity in the United States Clinical Antipsychotic Trials of Intervention Effectiveness Study Population

Cascella NG, Kryszak D, Bhatti B, Gregory P, Kelly DL, Mc Evoy JP, Fasano A, Eaton WW.

2Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 144, Baltimore, MD 21287.

Quote:

Celiac disease (CD) and schizophrenia have approximately the same prevalence, but epidemiologic data show higher prevalence of CD among schizophrenia patients. The reason for this higher co-occurrence is not known, but the clinical knowledge about the presence of immunologic markers for CD or gluten intolerance in schizophrenia patients may have implications for treatment. Our goal was to evaluate antibody prevalence to gliadin (AGA), transglutaminase (tTG), and endomysium (EMA) in a group of individuals with schizophrenia and a comparison group. AGA, tTG, and EMA antibodies were assayed in 1401 schizophrenia patients who were part of the Clinical Antipsychotic Trials of Intervention Effectiveness study and 900 controls. Psychopathology in schizophrenia patients was assessed using the Positive and Negative Symptoms Scale (PANSS). Logistic regression was used to assess the difference in the frequency of AGA, immunoglobulin A (IgA), and tTG antibodies, adjusting for age, sex, and race. Linear regression was used to predict PANSS scores from AGA and tTG antibodies adjusting for age, gender, and race. Among schizophrenia patients, 23.1% had moderate to high levels of IgA-AGA compared with 3.1% of the comparison group (chi(2) = 1885, df = 2, P < .001.) Moderate to high levels of tTG antibodies were present in 5.4% of schizophrenia patients vs 0.80% of the comparison group (chi(2) = 392.0, df = 2, P < .001). Adjustments for sex, age, and race had trivial effects on the differences. Regression analyses failed to predict PANSS scores from AGA and tTG antibodies. Persons with schizophrenia have higher than expected titers of antibodies related to CD and gluten sensitivity.
PMID: 19494248 June 2009
__________________

.
jccgf is offline  

advertisement
 


Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
Schizophrenia and gluten sensitivity jccgf Schizophrenia 0 03-02-2009 01:10 PM
gluten sensitivity in an infant? bizi Gluten Sensitivity / Celiac Disease 3 02-18-2008 10:19 PM
Gluten Sensitivity and Oats X post canoe Gluten Sensitivity / Celiac Disease 6 07-09-2007 09:22 PM
Gluten Sensitivity.net aklap Gluten Sensitivity / Celiac Disease 1 01-30-2007 11:19 PM
Myopathy and gluten sensitivity. jccgf Peripheral Neuropathy 0 12-06-2006 08:48 AM


All times are GMT -5. The time now is 06:38 PM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.