PAIN = STRESS, and chronic/intractable pain = chronic/intractable stress.

Aside from pain itself, many of the medications used to treat pain, including but not limited to ALL opioids, supress adrenal hormones, which negatively impact libido (desire).

Testosterone is just as important to women's libido as it is to men's - just in much lower levels.

Google: testosterone libido
Google: chronic pain hormone therapy

Properly balanced hormones can also have an effect on controlling/reducing pain itself, and a long list of other symptoms. It's a simple matter (blood test with fasting) to get levels on all the adrenal hormones, from pregnenolone (the "mother/master" hormone which is a precursor to all the adrenal hormones) on down to estrogen/testosterone, and then supplement the ones that are too low.

Doc

PS: Catma, don't forget to change your drawers!