Spinal Disorders & Back Pain For discussion of all spinal cord injuries, spinal issues, back-related pain or problems.


advertisement
Reply
 
Thread Tools Display Modes
Old 10-24-2006, 06:24 PM #1
shotspine shotspine is offline
Junior Member
 
Join Date: Aug 2006
Posts: 87
15 yr Member
shotspine shotspine is offline
Junior Member
 
Join Date: Aug 2006
Posts: 87
15 yr Member
Default Pls explain Oxy vs. Hydro

I seem to be fine with hydrocodone and hydromorphone but don't feel well with oxycodone or oxymorphone. Why?

Thanks!

ss
shotspine is offline   Reply With QuoteReply With Quote

advertisement
Old 10-24-2006, 08:53 PM #2
Kathi49 Kathi49 is offline
Member
 
Join Date: Sep 2006
Posts: 519
15 yr Member
Kathi49 Kathi49 is offline
Member
 
Join Date: Sep 2006
Posts: 519
15 yr Member
Default

Shotspine,

I can't really give you a CLEAR answer to that. But I am the same way. I do much better on Hydrocodone than the other. When I took Percocet before, I would get very nauseated. Hydrocodone does not do that to me and probably because it has more Tylenol in it which does not uspet the stomach. So, ONE Vicodin a day usually does the trick for me. Maybe someone will come along that has more experience with both.
Kathi49 is offline   Reply With QuoteReply With Quote
Old 10-24-2006, 09:57 PM #3
shotspine shotspine is offline
Junior Member
 
Join Date: Aug 2006
Posts: 87
15 yr Member
shotspine shotspine is offline
Junior Member
 
Join Date: Aug 2006
Posts: 87
15 yr Member
Default

Hi Kathy...

I don't think it's the tylenol because I take Norco 10/325...1/2 tab at a time so that has much less tylenol. Someone here should know though. Does Jim S post over here? He is a pharm tech and will know.
shotspine is offline   Reply With QuoteReply With Quote
Old 10-26-2006, 07:03 AM #4
Kathi49 Kathi49 is offline
Member
 
Join Date: Sep 2006
Posts: 519
15 yr Member
Kathi49 Kathi49 is offline
Member
 
Join Date: Sep 2006
Posts: 519
15 yr Member
Default

I take the Norco also; 7.5/325. I asked my NS the other day if, in fact, it works differently than Vicodin. He said yes, but did not go into great detail. It just seems that Vicodin works much better for me. I can take just ONE a day and I am good to go. With the Norco, I have to take 2-3 a day; normally just two. In any case, neither one of those upset my stomach. But Percocet will! I get nauseated and bad headaches with it. So, yes, maybe someone will come along and explain why.
Kathi49 is offline   Reply With QuoteReply With Quote
Old 10-27-2006, 12:14 PM #5
LizaJane's Avatar
LizaJane LizaJane is offline
Member
 
Join Date: Aug 2006
Location: Brooklyn, NY
Posts: 805
15 yr Member
LizaJane LizaJane is offline
Member
LizaJane's Avatar
 
Join Date: Aug 2006
Location: Brooklyn, NY
Posts: 805
15 yr Member
Default

Most people find oxy a bit stronger than hydro. That's all.
__________________
LizaJane


.


--- LYME neuropathy diagnosed in 2009; considered "idiopathic" neuropathy 1996 - 2009
---s/p laminectomy and fusion L3/4/5 Feb 2006 for a synovial spinal cyst
LizaJane is offline   Reply With QuoteReply With Quote
Old 10-27-2006, 06:09 PM #6
Tbackpain1's Avatar
Tbackpain1 Tbackpain1 is offline
Junior Member
 
Join Date: Aug 2006
Location: NY & PA (NE Phila.)
Posts: 38
15 yr Member
Tbackpain1 Tbackpain1 is offline
Junior Member
Tbackpain1's Avatar
 
Join Date: Aug 2006
Location: NY & PA (NE Phila.)
Posts: 38
15 yr Member
Default

On a chemical level, it has to do with the sites that each medication binds to (the mu opiate receptors) and the actions each has. If you'd like, I can go into the biochemistry, but the simple answer is that hydrocodone works slightly differently from oxycodone, but the end result of pain relief is similar.

Theresa
Tbackpain1 is offline   Reply With QuoteReply With Quote
Old 10-28-2006, 07:37 AM #7
sallyb sallyb is offline
Member
 
Join Date: Oct 2006
Location: louisiana
Posts: 143
15 yr Member
sallyb sallyb is offline
Member
 
Join Date: Oct 2006
Location: louisiana
Posts: 143
15 yr Member
Default full stomach

I think that taking the unsettling med with a full tummy would help. Also, Prevacid.
sallyb is offline   Reply With QuoteReply With Quote
Old 03-11-2008, 01:13 PM #8
opiatewizard opiatewizard is offline
New Member
 
Join Date: Mar 2008
Posts: 1
15 yr Member
opiatewizard opiatewizard is offline
New Member
 
Join Date: Mar 2008
Posts: 1
15 yr Member
Default chemical structure

It has to do with the way the molecules bind. The hydro molecules are hydrogen and the oxy is oxygen. Typically, people will tolerate both well or neither because they are both metabolized in the same location. However, in my circumstance, I can tolerate all opiates well including morphine. . .but, I have moderate allergic reactions to codeine.

So, when it comes down to it, it really depends on your body type and what you can tolerate.

As always, please be careful when taking any opiod analgesic as it can be hazardous to your health including addiction and/or fatal overdose.
opiatewizard is offline   Reply With QuoteReply With Quote
Reply


Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
How do colds and flu affect hydro? Spiritgal Hydrocephalus 14 09-20-2012 01:20 PM
hydro and menningitis mister Hydrocephalus 0 10-08-2006 04:06 PM
Please can you explain stumps Computers and Technology 10 08-31-2006 03:58 AM


All times are GMT -5. The time now is 06:32 PM.

Powered by vBulletin • Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.

vBulletin Optimisation provided by vB Optimise v2.7.1 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
 

NeuroTalk Forums

Helping support those with neurological and related conditions.

 

The material on this site is for informational purposes only,
and is not a substitute for medical advice, diagnosis or treatment
provided by a qualified health care provider.


Always consult your doctor before trying anything you read here.