Thoracic Outlet Syndrome Thoracic Outlet Syndrome/Brachial Plexopathy. In Memory Of DeAnne Marie.


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Old 01-26-2007, 11:36 AM #1
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gibbrn gibbrn is offline
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gibbrn gibbrn is offline
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Join Date: Sep 2006
Location: Calgary, Alberta...Canada!
Posts: 901
15 yr Member
Heart prayers and salbutamol info



Hi Di,

Just wanted to give you some info on the salbutamol before you go to the doc so you have more info.......my prayers are with you and yours
I hope you cry and continue to grieve well and don't hold back you need to let it happen and get it out
with love and support,
Victoria
Mode of action

As with other β2-adrenergic receptor agonists, salbutamol binds to β2-adrenergic receptors with a higher affinity than β1-receptors. In the airway, activation of β2-receptors results in relaxation of bronchial smooth muscle resulting in a widening of the airway (bronchodilation). Inhaled salbutamol sulfate has a rapid onset of action, providing relief within 5-15 minutes of administration.
In tocolysis, the activation of β2-receptors results in relaxation of uterine smooth muscle, thus delaying labour.


Adverse effects
While salbutamol is well-tolerated, particularly when compared with previous therapies such as theophylline, like all medications there exists the potential for adverse drug reactions to occur - especially when in high doses, or when taken orally or intravenously.
Common adverse effects include: tremor, palpitations and headache. (Rossi, 2004)
Infrequent adverse effects include: tachycardia, muscle cramps, agitation, hypokalemia, hyperactivity in children, and insomnia. [1]
The (S) isomer of salbutamol can inhibit the anti-inflammatory effect of steroids prescribed to treat asthma. However, the (R) isomer stimulates the steroid's effect and the overall effect of the two isomers is unclear[2].
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How poor are they who have not patience!
What wound did ever heal but by degrees.

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