ADHD - Aspergers Communication Impairments
 

Exploring Language Profiles for Children With ADHD and Children With Asperger Syndrome
http://jad.sagepub.com/content/16/1/34.full.pdf+html

Hi lara
 

These links are very interesting .I have just been reading your links on iron defiency and rang bells for me.My son was always low on iron and even had a alergic reaction to low iron where his body swelled and hives that was very big and left bruises.Im wondering if anyone else had low iron?

My daughter has constant problems maintaining normal Ferritin levels but she also has had extremely low B12 and has a few medical conditions that may play into all of this. She always only had very mild tics, more anxiety,ocd issues. I don't remember what my son's levels were. It wasn't something they were looking at way back then and any blood tests that were done routinely for him were Strep. related (GABHS). Both of them have immune system related issues. There also appears to be a link to Restless Leg Syndrome (yet another condition relating to dopamine dysfunction) which I have, although that's been very stable for me for a long time now thankfully.

EDITED to add: Katy, I'm just curious, but does your son have a gluten intolerance?

Hi lara:) not that i know he has bowel leakage problems and on med for that. I find the links very interesting lara and thankyou for putting your time in to deliver themxx

Anger control problems strongly correlated with comorbidity
 

Anger control problems are strongly correlated with comorbidity

J Am Acad Child Adolesc Psychiatry. 2003 Jan;42(1):98-105.
Disruptive behavior in children with Tourette's syndrome: association with ADHD comorbidity, tic severity, and functional impairment.
Sukhodolsky DG1, Scahill L, Zhang H, Peterson BS, King RA, Lombroso PJ, Katsovich L, Findley D, Leckman JF.
PubMed Abstract

J Am Acad Child Adolesc Psychiatry. 2000 Oct;39(10):1270-6.
Explosive outbursts in children with Tourette's disorder.
Budman CL1, Bruun RD, Park KS, Lesser M, Olson M.
PubMed Abstract

Dev Med Child Neurol. 2000 Jul;42(7):436-47.
An international perspective on Tourette syndrome: selected findings from 3,500 individuals in 22 countries.
Freeman RD1, Fast DK, Burd L, Kerbeshian J, Robertson MM, Sandor P.
PubMed Abstract

Can J Psychiatry. 1999 Dec;44(10):1036-42.
Aggressive behaviour in children with Tourette syndrome and comorbid attention-deficit hyperactivity disorder and obsessive-compulsive disorder.
Stephens RJ1, Sandor P.
PubMed Abstract

http://www.tsa-usa.org/Z_TSA_video/intro.html

VIDEO - TSA-USA

Tourette Syndrome: A Psychiatrist Talks to Parents about Anger -
John T. Walkup, MD

Books - Behavioural challenges
 

Greene, R. W. (2010).
The explosive child: A new approach for understanding and parenting easily frustrated, "chronically inflexible" children (Revised 4th edition).
New York: HarperCollins.

Greene, R.W. (2009).
Lost at school: Why our kids with behavioral challenges are falling through the cracks and how we can help them (Revised 2nd edition).
New York: Scribner.

Clinical Trial AZD5213
 

Wow, they seem to have jumped all over this very fast.

Just posting this Clinical Trial info. below as a follow up to the articles in a previous post which was...
HDC (Histidine Decarboxylase) gene

_____________

http://www.tsa-usa.org/aResearch/Saf...l_AZD5213.html

• Non-TSA Funded Study

Safety, Tolerability, Pharmacokinetic, and Efficacy of AZD5213 in Adolescents With Tourette's Disorder
Summit, NJ; Orange, CA; New York, NY; St. Petersburg, FL

http://clinicaltrials.gov/ct2/show/NCT01904773
Safety, Tolerability, Pharmacokinetic, and Efficacy Study of AZD5213 in Adolescents With Tourette's Disorder
This study is currently recruiting participants.

[Added note:
Sponsor:AstraZeneca]

_____________

http://www.prweb.com/releases/2014/03/prweb11637784.htm
March 05, 2014
- gives an explanation about how their drug targets histamine H3 receptor.
- dopamine regulation

_____________

I've just been doing some detective work and what do you know...

There's that T word again... Targacept

AstraZeneca quietly sweeps out some notable mid-stage drug programs
February 6, 2014 | By John Carroll
http://www.fiercebiotech.com/story/a...ams/2014-02-06

_____________

Targacept

http://neurotalk.psychcentral.com/post829509-71.html
Regarding Mecamylamine/Inversine etc.
TC-5214

Altered monocyte activation markers TS
 

from 2012 -

http://www.biomedcentral.com/1471-244X/12/29

Altered monocyte activation markers in Tourette’s syndrome: a case–control study

Judith Matz, Daniela L Krause, Sandra Dehning, Michael Riedel, Rudolf Gruber, Markus J Schwarz and Norbert Müller



BMC Psychiatry 2012, 12:29
doi:10.1186/1471-244X-12-29

This is an Open Access article distributed under the terms of the Creative Commons Attribution License

Iron Deficiency Anemia
 

Interesting

http://www.biomedcentral.com/1471-244X/13/161

Association between psychiatric disorders and iron deficiency anemia among children and adolescents: a nationwide population-based study

Mu-Hong Chen, Tung-Ping Su, Ying-Sheue Chen, Ju-Wei Hsu, Kai-Lin Huang, Wen-Han Chang, Tzeng-Ji Chen and Ya-Mei Bai