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Old 05-22-2009, 03:29 PM #51
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Default Genomic profiles for human peripheral blood T cells, B cells etc...

PubMed

Genomics. 2006 Jun;87(6):693-703. Epub 2006 Mar 20
Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome.
Du X, Tang Y, Xu H, Lit L, Walker W, Ashwood P, Gregg JP, Sharp FR.
MIND Institute, University of California at Davis
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Old 05-22-2009, 03:33 PM #52
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Default OCD - Immunological alterations

old abstract - 1999

PubMed
Biol Psychiatry. 1999 Sep 15;46(6):810-4.
Immunological alterations in adult obsessive-compulsive disorder.

Marazziti D, Presta S, Pfanner C, Gemignani A, Rossi A, Sbrana S, Rocchi V, Ambrogi F, Cassano GB.

Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, University of Pisa, Italy.

Quote:
CONCLUSIONS: These data indicate that patients with adult OCD showed increased CD8+, i.e., suppressor T lymphocytes, and decreased CD4+, which identify helper T lymphocytes, as compared with a similar group of healthy control subjects. The findings appear peculiar to patients with OCD and are suggestive of an immunologic imbalance, which might be related to the stress deriving from the frustrating situation determined by the disorder itself.
Then again...

PubMed
Psychiatry Res. 2001 Nov 30;104(3):221-5.
The use of antibody D8/17 to identify B cells in adults with obsessive-compulsive disorder.

Eisen JL, Leonard HL, Swedo SE, Price LH, Zabriskie JB, Chiang SY, Karitani M, Rasmussen SA.
Department of Psychiatry and Human Behavior, Butler Hospital, Brown University School of Medicine,

Quote:
Compared with healthy control subjects, individuals with childhood-onset obsessive-compulsive disorder (OCD) have been reported to have a higher percentage of B cells that react with the monoclonal antibody D8/17, a marker for rheumatic fever. This study sought to replicate these findings in adults with OCD. Double-blind analyses of blood samples from 29 consecutive adults with primary OCD and 26 healthy control subjects were conducted to determine the percentage of B cells identified by D8/17. Using a standard criterion of > or =12% labeled B cells to denote positivity, rates of D8/17 positive individuals did not significantly differ between the OCD (58.6%) and control (42.3%) groups. Early age of onset was not a predictor of D8/17 positivity in the OCD group. The percentage of B cells identified by the monoclonal antibody marker D8/17 did not distinguish adults with OCD from control subjects, nor did it distinguish a sub-group of adults with OCD who described pre-pubertal onset of their OCD symptoms.
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Old 05-22-2009, 03:47 PM #53
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Default Full Text of 2006 TS genome scan

PubMed Central Full Text Article

Am J Hum Genet. 2007 February; 80(2): 265–272.
Published online 2006 December 12.
PMCID: PMC1785345

Genome Scan for Tourette Disorder in Affected-Sibling-Pair and Multigenerational Families
The Tourette Syndrome Association International Consortium for Genetics
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Old 05-22-2009, 04:16 PM #54
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Default superantigen hypothesis

excerpt from Book...

Tourette's syndrome--tics, obsessions, compulsions
By James F. Leckman, Donald J. Cohen (1998)

from Google Books
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Old 05-22-2009, 04:23 PM #55
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Default Functional Disturbances Within Frontostriatal Circuits

PubMed
Am J Psychiatry. 2009 May 15.
Functional Disturbances Within Frontostriatal Circuits Across Multiple Childhood Psychopathologies.
Marsh R, Maia TV, Peterson BS.

<snipped abstract>
Quote:
Conclusions Analogous brain mechanisms in parallel frontostriatal circuits, or even in differing portions of the same frontostriatal circuit, may underlie the differing behavioral disturbances in these multiple disorders, although further research is needed to confirm this hypothesis
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Old 05-22-2009, 04:26 PM #56
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Default Prefrontal and anterior cingulate cortex abnormalities (VBM) (MTI)

Note: small sized study.

PubMed

BMC Neurosci. 2009 May 12;10(1):47.
Prefrontal and anterior cingulate cortex abnormalities in Tourette Syndrome: evidence from voxel-based morphometry and magnetization transfer imaging.
Muller-Vahl KR, Kaufmann J, Grosskreutz J, Dengler R, Emrich HM, Peschel T.
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Old 05-22-2009, 04:32 PM #57
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Default stimulus evaluation, response inhibition and motor processing

PubMed
Psychiatry Res. 2009 May 30;167(3):202-20.

Electrophysiological manifestations of stimulus evaluation, response inhibition and motor processing in Tourette syndrome patients.
Thibault G, O'Connor KP, Stip E, Lavoie ME.

Centre de Recherche Fernand-Seguin and Hôpital Louis-H. Lafontaine, Montréal, Québec, Canada; Département de Psychologie, Université de Montréal, Montréal, Québec, Canada.
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Old 05-22-2009, 04:35 PM #58
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Red face Long needle acupuncture

PubMed

Zhongguo Zhen Jiu. 2009 Feb;29(2):115-8.Links
Clinical study on scalp acupuncture with long needle-retained duration for treatment of Tourette syndrome
[Article in Chinese]
Zhu BC, Shi-fen X, Shan YH.
Department of Acupuncture, Shanghai Hospital of TCM, Shanghai
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Old 05-22-2009, 04:38 PM #59
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Default The behavioral spectrum of Gilles de la Tourette syndrome.

PubMed

J Neuropsychiatry Clin Neurosci. 2009 Winter;21(1):13-23.
The behavioral spectrum of Gilles de la Tourette syndrome.
Cavanna AE, Servo S, Monaco F, Robertson MM.

Sobell Department of Movement Disorders, Institute of Neurology, London, UK.

<snipped abstract>

Quote:
This paper provides an updated review of the literature on the multifaceted phenotype of Tourette's syndrome, with special attention to the behavioral problems and the relationship between Tourette's syndrome and comorbid neuropsychiatric conditions. The issue of whether Tourette's syndrome should still be considered as a unitary nosological entity is also addressed.
NOTE: http://neuro.psychiatryonline.org/cg...stract/21/1/13
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Old 06-11-2009, 08:10 AM #60
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Default Stuttering (from my bookmarks)

http://www.ncbi.nlm.nih.gov/pubmed/10907717
J Commun Disord. 2000 May-Jun;33(3):227-39;
Dysfluency and phonic tics in Tourette syndrome: a case report.
Van Borsel J, Vanryckeghem M.

http://www.mnsu.edu/comdis/isad2/papers/molt2.html
The Basal Ganglia's Possible Role in Stuttering: An Examination of Similarities between Stuttering, Tourette Syndrome, Dystonia, and other Neurological-Based Disorders of Movement
by Larry Molt

http://www.mnsu.edu/comdis/isad6/papers/donaher6.html
Disfluency Associated with Tourette's Syndrome: Two Case Studies
by John Tetnowski and Joseph Donaher

http://www.stutteringhelp.org/Default.aspx?tabid=440
Stuttering and Tourette's Syndrome
This material was compiled by Luc De Nil, Ph.D., Chair of the
Graduate Department of Speech-Language Pathology, University of
Toronto, and by Paul Sandor, M.D., Director of the Tourette’s
Syndrome Clinic, University Health Network.

http://www.cmaj.ca/cgi/content/full/162/13/1849
Stuttering: an update for physicians
Daniel Costa and Robert Kroll

http://www.ncbi.nlm.nih.gov/pubmed/15856831
Rev Laryngol Otol Rhinol (Bord). 2004;125(5):297-301. Links
Stuttering and Tourette's syndrome: a short tutorial and account of a four years experience in a stuttering clinic constriction of the vocal tract
[Article in French]
Monfrais-Pfauwadel MC.
Hopital Europeen Georges Pompidou, AP-HP, Paris, France

Quote:
The author presents a short tutorial of Gilles de la Tourette's syndrome followed by a state of the art of review of the clinical links between stuttering and the different kinds of Tourette and tics disorders. The author relates her own experience of working for four consecutive years at the new stuttering diagnostic center at the "Hopital Europeen Georges Pompidou ". The article ends with a practical review of the actual therapies available when such a diagnosis is made.
http://www.mnsu.edu/comdis/isad6/pap...fauwadel6.html
Differential Diagnosis of Stuttering and Self-referral
by Marie-Claude Monfrais-Pfauwadel
from France

http://www.unboundmedicine.com/medli...t=10&prev=true
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