I have been taking about 300-400 mcgs of B-12 on a full stomach for years and have good blood concentrations. My suggestion is take enough to get the blood concentration to about 1000 pcgs/mL.

I mention the spirulina because many vegans/vegetarians claim to get all they need from their normal vegan diet. Studies show some serious deficiencies in the vegetarian diet.

You are lucky.....you must still have some intrinsic factor activity.
This however can be blocked in many people who use acid blocking drugs for heartburn, or who have poor acid levels in the stomach due to genetic errors in intrinsic factor activity, or who are older. The presence of food in GI tract (small intestine) tends to absorb microgram amounts of certain drugs like digoxin and thyroid hormones. Studies have found poor absorption of microgram type doses.

There is a study done by a doctor measuring absorption under ideal conditions...of B12 and it is very small. About 13mcg for a dose of 1000mcg, on an empty stomach.
So unless everyone gets B12 tests periodically, they will never know if they are absorbing properly unless they take it on an empty stomach.

Here is the paper...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2532799/

and the link to his table with doses:
http://www.ncbi.nlm.nih.gov/pmc/arti...able/T1/#TF1-4

In the younger age groups who post here, it is less common
to have low B12 unless the person has a terrible diet or is anorectic, or has the genes for pernicious anemia.

But for many of the posters on NeuroTalk, the empty stomach is
important.

Also another point... about 10-30% of the population has been found to be unable to methylate B12 and folic acid. This failure means that cyanocobalamin form will not work for them.
They require methylfolate and methylcobalamin for supplementation therefore. The 23andme website has now lowered its price again for DNA testing for this genetic error, and it is now $99. (for those interested.)

Those with Celiac and/or gluten intolerance, and those with inflammatory bowel diseases, malabsorption of B12 does occur.
So B12 is not a simple thing to supplement when all these factors may be present.

Mark - do you take your supplements at a certain time of day? I take mine with breakfast and have always wondered if that is ideal for the PCS brain or if it should be spread out over the course of the day. I take a Multivitamin, Vit C, D3, and probiotics.

Thanks

I take my full regimen after breakfast. I sometimes will eat half a banana after to push any stragglers down. Some tend to get stuck in my esophagus going down.

Musiclover, You regimen looks very weak. Most multi's are based on the RDA and are very weak on B's and folic acid. You also need strong minerals.

Hi guys! Mark, as an avid fitness enthusist and gym goer, I like the supplement list that you have posted in the first post. I take most of these on a regular basis

Hey guys, just to add on to Mark's first post, If you do a google search for NOW Foods supplements they are made with the highest purity, no filler products, and are very cheap.

For multi-vitamin: NOW FOODS ADAM
For Chlorella: NOW FOODS CHLORELLA
For Spirulina: NOW FOODS SPIRULINA

I have never taken the second and third product ever. But I have ordered some and just received them. I am going to start next week. I stumbled upon these products because I had 3 CT scans for my head in a span of four months. Two of those three were 7 days apart. I am worried about all the radiation that I have absorbed and apparently taking chlorella + spirulina absorbs and takes away a good amount of the negative effects of the radiation if taken over time. There are good research articles on google where these products were given to children of the chernobyl incident and within a few months their radiation levels dropped significantly.
These two supplements are also considered detoxing agents and people in the supplement reviews on various supplement websites have reported having more energy and feeling young and rejuvenated again. I will try to post my experiences with them after I have taken them for about 90 days or so.

What about DHEA, Mark?

Is it safe? What do you use it for ,exactly?

Did you see any objective improvements by taking it?

In Canada i think it is considered a steroid and therefore impossible to find because of safety reasons...

Pepa

Mark,
Thanks for this. The link to the video was great. Yeah we look good but we are not good. My mom always says that she thinks that is why I was denied disability because I look too good. I have been very sick for a long time though. To me, I don't look good. I can see the toll this has taken. Black under my eyes etc. I guess others don't notice, they are only changes we can see.
Thanks again this was helpful and I am trying to get a good vitamin plan going. I pretty much have to use what is here in the house as I am broke and can't afford to go buy the kinds I need.
Hope you are all having a good day or hour or minute.
Love,
Brain

Mark

Thanks for posting this, and repeatedly promoting it. It should surely be a sticky in here?

I have just ordered everything suggested at a cost of £70 (no turmeric extract though). This should last 3 months minimum.

I'll let you know how I get on.

Here is a new video on vitamin B12 issues. It only touches on the methyl form near the end, and that is its only weakness.

http://neurotalk.psychcentral.com/thread85103.html
This thread will provide that information where the video leaves off.

http://www.youtube.com/watch?v=BvEiz...ature=youtu.be

I'm not sure if I should post my own vitamin regimen here. So please feel free to delete . Anyway, my own vitamin regimen is based off of Mark's. Thank you Mark for the guidelines! I will be seeing a Chiropractic Neurologist next week and see what he says as well with regard to my regimen.

I've only started on them for a week and I think I do need to refine it and maybe i'm taking too much. So please feel free to reply with your opinions. Thanks for your support.

Daily Vitamin Regimen

Omega 3 Nature Made 1200 mg x 4
Garden of Life Vitamin Code Multi x 4
Vitamin C 1000mg x2
B Complex 100 x2
Vitamin Dry A 10000IU x2
Vitamin D3 5000IU x2
Tumeric Supreme (Gaia Herbs) x2
New Chapter Organics Cal Mag Health x3
Garlic Tablet x1
Probiotic x1
Zyflamend (New Chapter) x2 (I'm not sure if this will help but it says it will help with body inflammation but maybe more for joints? Just saw it at Whole Foods and decieded to try it)
Arnica Montana x5 twice a day (Homeopathic)

Just picked this up today : Jarrows NeuroOptimizer (Havan't tried it yet. But it says it promotes brain health and functioning but not sure if it's for my more specific migraines) Also picked up SuperNutrition Anti Oxidant Power. There are so many antioxidant formulas out there but this one seemed more complete. Is an antioxidant formula helpful for PCS? Not sure! I need guidance! Thanks

Feverfew (read that it's good for migraines) as needed.

I'm not sure if Brand of Vitamins actually makes a difference? I'm thinking of switching my Fish Oil brand to the Garden of Life Mor-O3 (Minami Nutrition) which describes itself as a supercritical O3 Fish Oil in Triglyceride Form.

Anyway please comment! I'm not really too sure about my dosage levels as well. My dosage levels are all according to recommended serving size except for the fish oils and vitamin C which i'm doubling up on. Thanks.

As well should I be taking a separate Magnesium Citrate? (read it's good for migraines)

Thank you for your support.