Traumatic Brain Injury and Post Concussion Syndrome For traumatic brain injury (TBI) and post concussion syndrome (PCS).


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Old 04-04-2015, 05:26 PM #1
cholesterol cholesterol is offline
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Default Cholesterol Levels

Hi guys, I 'm new here. Could you please let me know your cholesterol levels? If you don't mind, what are the values, I 'm mostly interested in HDL-C and TC (Total Cholesterol). I hope everyone is doing well. If anyone wants to talk to me about any issues experiencing, more than welcome.
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Old 04-05-2015, 03:21 PM #2
Mark in Idaho Mark in Idaho is offline
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cholesterol,

Welcome to NeuroTalk.

Have you suffered a concussion or TBI ?

Are you concerned that cholesterol levels effect recovery ?
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Old 04-05-2015, 03:34 PM #3
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Welcome cholesterol.
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"It is what it is."
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Old 04-05-2015, 04:44 PM #4
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Quote:
Originally Posted by Mark in Idaho View Post
cholesterol,

Welcome to NeuroTalk.

Have you suffered a concussion or TBI ?

Are you concerned that cholesterol levels effect recovery ?

Mark thanks! I 've suffered a concussion yes. Not exactly what you wrote. I 'm concerned that altered membrane cholesterol prevents recovery. Or better - I am convinced, not concerned... But I 'd like to know what I asked. It's true that sometimes serum cholesterol levels might look fine, but (CSF) membrane cholesterol might be low. I know this has been proposed as a cause of depression (and a side-effect of statins). Recently I found evidence how low membrane cholesterol prevents glutamate reuptake by cells. I 'd love to know the levels though (of people with PCS). Actually the pre-injury would make more sense.
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Old 04-05-2015, 04:59 PM #5
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Quote:
Originally Posted by Kitt View Post
Welcome cholesterol.
Hello, thank you.
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"Thanks for this!" says:
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Old 04-05-2015, 06:37 PM #6
Mark in Idaho Mark in Idaho is offline
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How would one know if CSF membrane cholesterol is low ? Is there a test for that ?

I read long ago that low cholesterol increases the risk of Alzheimer's.

I know my cholesterol is not great. The bad cholesterol is not great and the good cholesterol is not great. My total is OK by old standards but not newer standards. I bet most of us do not have quick access to the numbers.

A quick review of the literature suggests that highly unsaturated fatty acids are more involved. Also, the blood brain barrier blocks circulatory cholesterol from entering the brain. CNS cholesterol is synthesized on the brain side of the blood brain barrier.

There is a lot to read on this issue. Fatty acids are well know as needed for good brain health.

I think I am with you at wondering if low fat diets contribute to concussion risks. I have never held to a low fat diet. We just avoid the bad processed fats. I read an article about oxidized cholesterol and try to limit it.
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Old 04-06-2015, 05:31 AM #7
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Mark cholesterol is NOT synthesized SOLELY in the brain. Apolipoprotein A1 crosses the BBB and plasma Apo-A1 is elevated after TBI and predicts short term outcome. Oxysterols also cross the BBB.
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Old 04-06-2015, 10:01 AM #8
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Here are two of the articles I found. I guess I misunderstood what they said.

http://www.hindawi.com/journals/chol...l/2012/292598/

http://www.ncbi.nlm.nih.gov/pubmed/10617992
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Old 04-09-2015, 11:25 AM #9
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Following this - it is an interesting question. There is a link between low cholesterol and autism as well. I never heard about the Alzheimers thing. It runs in my husbands family but so does high cholesterol. Hmmmm
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