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Traumatic Brain Injury and Post Concussion Syndrome For traumatic brain injury (TBI) and post concussion syndrome (PCS). |
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01-04-2020, 01:08 AM | #1 | ||
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Member - formerly TT1234
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I've been reading a bit about PCS, inflammation, and the endocrine system. Especially about possible connections between testosterone and PCS. It then struck me that the vast majority of people who report sensitivity to bumps here are young men -- and all but one that I know of have been men.
If there is real a correlation here, it might suggest a link between some dysfunction of the male sex hormones and sensitivity to bumps. I think it would be interesting to (informally, unscientifically) confirm this suspicion. Thus, I'm hoping that some people with sensitivity to bumps might report in with their sex and age of onset of sensitivity to bumps. |
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01-04-2020, 10:44 PM | #2 | ||
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Junior Member
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This happened to me and i wonder the same thing. I am a young man with the same issue. The only issue is i got my testisterone tested and it was 699 (maybe thats low for me?). I dont habe libido issues (maybe at first) however i did lose about 15 lbs of muscle weight within 2 mths of tbi. Sometimes i wonder this and if my testosterone was normally just high.
I tried clomid and had some shitty side effects: floaters, brain fog, etc. It felt good the first couple days then went down hill. I did this supplement called red beast and felt good on that, however only recommended for short term use. I am considering long term products however want to maintain fertility (only have one kid thus far). |
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01-05-2020, 01:52 AM | #3 | ||
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Legendary
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I've had my T tested a few times. The most recent said the prior tests that suggested low T were wrong. The tests were not done properly. A proper test done by averaging multiple tests showed I was high T.
When I had tried T cream, I was all messed up. Acne, oily skin, and other symptoms of excessive T..... I was sensitive to bumps in my 50s. My sensitivity resolved about the same time my neck gained stability. I have other concussion symptoms, memory, cognition, and other processing struggles that have remained with no improvement. The bumps created a sense similar to being over-stimulated. That bump trigger is gone but I can still be over-stimulated by too much auditory stimuli. (too much for me)
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01-05-2020, 10:34 AM | #4 | ||
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Junior Member
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Female.
Age of onset: 24, right after a bad bike crash I have not had any issues with bumping my head (which I have bumped it plenty of times since the bike crash, as most people do). Only have had issues with sudden change in speed of head movement (falls, hitting very large potholes in the car, etc.) Also, all linear motion feels exaggerated compared to what I would expect to feel. Walking used to feel like a violent rollercoaster ride when this symptoms was at it's worst. |
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01-06-2020, 11:55 PM | #5 | ||
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Junior Member
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I am a 17 year old male as well. I have been on Clomid for around 8 weeks in hopes to improve my sensitivity to bumps. I am very confused currently because, while on Clomid, I still experience symptoms at a lesser degree, but when I abstain for a couple of days, I really notice the difference. I do not think the window of tolerance to forces has improved, just the symptoms endured. MrPCS has really promising posts about his son improving.
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01-07-2020, 12:24 PM | #6 | ||
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Member - formerly TT1234
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04-10-2020, 05:04 PM | #7 | |||
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Junior Member
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Well i’m very late on this one.
It may actually be the other way around. I read a study some time ago done on rats where they tested out many different things. One of the things they did was give male rats high doses of estrogen before inducing a concussion in the them. They then noted behaviour and mortality rates. The male rats that had been giving estrogen recovered faster and the mortality rates were lower. They theorised that estrogen may have neuroprotective/ anti inflamatory properties. The weird things is when they gave the female rats estrogen it worsened their recovery times, and increased the mortality rate. Maybe estrogen is good up to a certain level, where it becomes too much and then counter productive? Ofcourse rats and humans are different, so it may be completely non applyable but still interresting. |
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04-15-2020, 10:36 PM | #8 | ||
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Member
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Interesting stuff, Atlas.
Have you looked into other biochemical connections with brain injury? |
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04-16-2020, 07:07 AM | #9 | |||
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Junior Member
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No not really, i read it by random chance awhile ago.
I’m not extremely knowledgeable in this at all, i only started looking into all this stuff when i got my concussion, which was relatively recently. I won’t pretend i have read the whole thing, i’ve just skimmed the interesting stuff. I’m currently not able to post links it seems, because my post count is below 10, but the study is called “Neuroprotection by Estrogen and Progesterone in Traumatic Brain Injury and Spinal Cord Injury” - by Evgeni Brotfain, Shaun E. Gruenbaum, and Moti Klein Here is the part I referenced “Emerson and colleagues reported that estrogen administration before TBI improved neurological outcome in male rats, but paradoxically worsened neurological outcomes in female rats [9]. Zlotnik and colleagues further demonstrated that injection of premarin (mixture of estrogens) in male rats after TBI resulted in a significant decrease in blood glutamate concentrations and improved neurological outcomes [10]. Furthermore, Neese and colleagues demonstrated the pretreatment with Z-BDDA (estrogenic seco-steroid) resulted in a significant improvement in learning and memory tests after moderate TBI [6].” |
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"Thanks for this!" says: | JBuckl (04-18-2020) |
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