Vitamins, Nutrients, Herbs and Supplements For discussion about vitamins, vitamin deficiency, herbal remedies and other supplements.


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Old 09-19-2006, 10:49 AM #11
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Red face Hey, Alicia...

I did a search and found this....

http://www.indianpediatrics.net/nov2...-1175-1179.htm
Quote:
Dietary manipulations including high carbohydrate intake has been recommended to compensate for impaired gluconeogenesis and to decrease lipolysis. Anecdotal success has been reported with a number of vitamins and co-factors [riboflavin, vitamin K, vitamin C(12, 13), thiamin, nicotinamide, carnitine] and glucocorticosteroids. Coenzyme Q10 has been used most extensively in varied doses (10-120 mg/day) and found to be more consistently beneficial in some studies(14) clinically and on investigation (decrease in serum lactate, nerve conduction velocities, muscle metabolism measured by magnetic resonance spectro-scopy). On the other hand other workers obtained no response.

In conclusion, neurological mitochondrial disorders in children have a wide range of age of onset and clinical manifestations. Heightened awareness of these disorders would help towards proper diagnosis and treatment in many previously undiagnosed cases.
Your situation is highly specialized, with new data coming in all the time.
So I certainly am not "up there" except for what I can find on the net.
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Old 09-19-2006, 02:22 PM #12
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Quote:
Originally Posted by KTM5665 View Post
whatchya know about mito and vitamin K, Mrs D?! twins started on it recently. I have read it needs to be combined with vitamin c. Thoughts?
This may not be exactly what you are looking for as I suspect you are mainly looking for information for children, but here’s some quick Vit K info from more of a technical standpoint (I covered some Vit K info in my research):

3 types of Vitamin K:
K1 (phylloquinone): Mainly controls blood coagulation.
K2 (menaquinones (MK-4 (menatetrenone) through MK-10)): Help control calcium uptake in bones & controls calcium levels in bloodstream (via osteocalcin, etc. carboxylation).
K3 (menadione): Synthetic and generally not recommended for supplementation.

Some good Vit K links (general info):
http://www.lef.org/magazine/mag2000/feb00-report.html
http://www.lef.org/magazine/mag2004/mar2004_aas_01.htm
http://www.lef.org/magazine/mag2002/...t_vitk_01.html
http://www.pdrhealth.com/drug_info/n...vit_0267.shtml
http://en.wikipedia.org/wiki/Vitamin_K

Some good research studies (Medline/PubMed, full text documents are available for these). Vit K2 appears to do a very good job with bone health (osteoporosis) and alleviating arteriosclerosis:
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum
http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum

Lots of additional research is currently being performed with Vit K. From what I gather, it appears that adequate Vitamin D (but not overdoing it) is needed for appropriate calcium absorption, and then Vitamin K (K2) puts calcium where it needs to be… in the bones.

P.S.
A suggestion for this forum might be to have specific threads dedicated to technical/research/reference information for each vitamin/nutrient. Threads could be labeled, for example, “Vitamin K, Research Data” or “Vitamin K, Reference Information” and appropriate links to research/reference documents, etc. could be posted in these threads. We could still keep the “Useful Websites” sticky reserved for overall reference databases/knowledgebases (for ex. drug-vitamin/nutrient depletion references, etc.). Perhaps this will help keep the information organized. Any thoughts?
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Old 09-19-2006, 03:22 PM #13
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Lightbulb yes, west, I agree...

I am already planning B6 thread, EFAs (Omega-3), Magnesium, Zinc,
and Carnitine.

If you want to do K, which you seem to have alot of info on already, and
D, you could get rolling on those.

Common Vits, are covered very heavily on Linus Pauling Institute, and
don't really need their own thread here, I don't think.

But I do think that threads like Nutritional support for Fibromyalgia,
Lymes, Osteoporosis, Cancer (chemo damage), seizures, MS, would be valuable. People with those issues usually look for their illness rather than individual nutrients.

There's plenty to keep us busy for a while!
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Old 09-19-2006, 03:45 PM #14
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Great forum , thank goodness its here, can you also please cover vitamins individually such as Thiamine, riboflavin, carnitine, D-ribose and such..with more and more having a suspected mito dysfunction or metabolic illness it could be really helpful. The multi vitamin approach is broken down in mito and metabolics (adults)a lot more. and I get muddled.
In the UK were I am they told us a few weeks ago Mitochondrial Cytopathy in general is possibly the most under-diagnosed condition in our country today..Will be appearing on various forums as at present finding this smaller set-up easier to use.
Gillian
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Old 09-19-2006, 03:53 PM #15
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Lightbulb Gillian...

Please check out that link I posted for Alicia...it covers the mito/nutrient
issue for patients with mito issues.

Nice to see you here!
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Old 09-19-2006, 04:16 PM #16
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MrsD and west1~

what great sources of info you both have provided. I'm going to have a field day, reading all of this. I really appreciate the time you both have spent today, and in the past helping me! Looking forward to a great read!!!!!
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~Alicia~who feels that four kids with a mitochondrial disease is like patching the Titanic with a bandaid at times, but I say.."SHUT UP, Sit Down and ROW"...
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Old 09-19-2006, 04:50 PM #17
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I am soooo happy to see this forum. May it grow in leaps and bounds I haven't read much of it yet nor do I have any input......except.........THANK YOU!!!!! Right now I am goofy as heck from side effects of nortriptyline. My Doc told me to increase by 1 each day until 1)pain relief 2)side effects or I hit 10per day. Well, today is the aftermath of taking 6 last night. S/E hit like a ton of bricks today so have call into Dr.

Guess why I am taking these to start with!! Sit down first.........I tried to get my insurance co to preauthorize LIDODERM patches. They won't until I try all of the following: Neuorontin, Nortriptyline, Cymbalta, and Fentanyl and one other I can't remember. My Dr and I are furious as none of this makes any sense. He says: "when they see the word 'patch' they will make you go thru all the 'cheaper' drugs thinking all patches are the same. Good God! Well, gotta run, I'm not feeling so great. Will sure be back and use this forum a lot!

Hugs and Blessings to all!
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Old 09-19-2006, 05:53 PM #18
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Red face Whoa...shotspine...

Welcome here friend.

I sure hope that is the 10mg nortrip you are on that you are increasing!

I really don't understand insurance companies...they just torture the patients.

Cymbalta, and fentanyl are not good medical interventions. Cymbalta is expensive and Fentanyl is habit forming... The others are available generically and I can see a tier thing with them. But the other two just defy logic.

Lidoderms are expensive, but I think fentanyl is comparable or even less. I feel really lucky to get 90 Lidoderms/90 days for $35.00. And more than lucky since I haven't had to use them lately... but you never know!

You should contact your insurance and ask about prior authorization procedures.
Some have in place policies to allow your doctor to by-pass some of the rules.

Take care.
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Old 09-19-2006, 07:12 PM #19
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((((((((((((((((((((mrsd))))))))))))))))))))))

Oh I am one happy lady to see you! I can't tell you how many times I kicked myself this summer for not having your email addy. So, will you please PM me with your addy. Generally, I find all I need from looking thru your posts and never thought about the fact that you AND posts would just go "poof". I don't even remember what was so important, but it was at the time and I felt so ..........sad, and left to fend for myself. Not that I haven't done that all my life but hey, when you find a lifeline that is just a click away.....laziness creeps in and so does fear of 'who to trust now'.

Anyway, yes it's 10 mg. Still waiting for a call back. I'm still goofy as all get out too so will be back. And yes, I know what you are saying......I'm going to fight before I have to take the Cymbalta. I already lied and said I couldn't take Neuorontin (I had RX's for it that I filled but never took. I have had samples of Cymbalta for a year or more and haven't tried it yet and don't want to. Fentanyl, I have several patches left over from before my Dad died in 03. I've never tried them and don't want to. I already take Dilaudid and Methadone. I don't NEED oral/internal meds. I NEED local lidoderm patches. It is really very scary to realize that the people at the ins. co. know NOTHING about medication. I mean really......this could be serious for those that don't know better. Fentanyl inlieu of lidocaine??? That could really do a number on some.

Okay, that's my grief and I'm worn out ................just so happy to be back. Hope you had a terrific summer mrsd!!!
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Old 09-19-2006, 07:44 PM #20
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Default Re: yes, west, I agree...

Quote:
Originally Posted by mrsd View Post
If you want to do K, which you seem to have alot of info on already, and
D, you could get rolling on those.
Thanks mrsd. I will try to kick off some threads for these as I get a chance. I probably now have hundreds of bookmarks for studies, etc. that I have come across for various vitamins/nutrients (as well as meds/issues) and would need to go through them again to pick out the best ones to post. As mentioned previously, the (large) update that I wanted to post on the thread I started on OBT/BT1 has some good info, but not having the whole thread here would make the update hard to follow (unclear). I would otherwise have some major rewriting on the update to make it make sense and with the passage of time, even the update itself will eventually become obsolete.

Thanks again. I will try to have something up within the next few days.
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