I'll probably post more later, but wanted to get something down as soon as possible.
I'm a long term migraine sufferer. I also have a history of lupus, which according to tests is in remission.
Several years ago, I began taking Topamax to treat my migraines and this caused some foggy thinking...which is normal for this medication.
However, over the last few years, the foggy thinking worsened, even though I lowered my Topamax dosage. I've had increasing fatigue, even though my lupus tests are negative. I've had problems with my hair falling out and severe memory loss.
I take a vitamin B Complex and my level is 600. I understand this is a normal level. My neuro wanted me to take 1000 mcgs of b12. At first I rejected the idea; figuring that since my levels were normal, it wasn't necessary.
However, I did note that I'm taking an anti-seizure medication, I'm gluten sensitive and I have stomach problems and take a medication to treat it. These are all things that can interfere with b12 absorption.
About two weeks ago he insisted that I take the b12. No debate, etc.
He gave me a shot (no charge) and that was that. said to take 1000 mcg. at home. No further instructions.
That afternoon after the shot, I had more energy than usual.
But the next day...zippo.
Then I started the b12 pills.
For a week zippo.
But GUESS WHAT? All of a sudden, I have more energy again. MORE ENERGY THAN I HAVE HAD IN YEARS.
I'm taking the one that starts with a "c"
However, U just purchased Methyl B12 from Jarrow. It is a lozenge. Several people have said that the methyl is considered better quality. One concern I have is that it has lemon flavor and other things in it that might interere with my migraines, since I seem to be ultra sensitive to food triggers.
Can anyone else recommend a very specific b12?
Just wanted to mention that your numbers might not be a true indicator of what is going on. I'm convinced that I really do need this b12 supplementation and am very grateful that my doctor insisted that I try this.

And I think your doctor must be exceptional! Maybe he reads US?

There are other brands...Source Naturals has a cherry flavor.
But you know, you can swallow it whole, it will work that way too.

You need not chew them or put them under the tongue.

That is great you are doing better. Rose will be happy!

Mrsd -- does it matter if the B12 is not the Methyl B12 'stuff' ?
I'm still concerned because 1,000 mcg. seems so high.
I had been taking 1/2 of a 300 mcg tablet each day until a couple weeks ago when I accidently bought the bottle of 1, 000 tablets. Since then I haven't taken any.
Many thanks for your help.
VL -- it's wonderful that you're feeling better and have ENERGY !! I have hope.

Hello Jingle...

The reason methylcobalamin is being recommended now, is that genetics
research is showing that people often do not convert cyanocobalamin effectively to get full benefit. Cyano is a synthetic man-made version, it is the most commonly known for many years, and requires 4 steps in the body so that
the body can use it.

The trend today is that using the methyl (which is very inexpensive now...9 cents a day) is the most guaranteed oral way to go. In fact the new RX version Metanx has the new methyl in it, and we will see this take over from the cyano.

Now dose wise... when B12 is used orally this way very little is absorbed.
It is thought that about 10 micrograms out of the 1000mcg in a tablet are successfully passively absorbed in the small intestine. The rest is lost.

Since no physical toxicity has ever been seen with high dose B12, the concern for doses is not a real factor for worry. Taking too little is more of a worry in fact!

Thank you mrsd. I'll take the 1000 mcg (from Sam's Club ) with confidence. And next time I'm in a city I'll look for some methyl.

I have not seen the methylcobalamin locally commonly. Most of us who
use it, buy it on line. Our favorite place is www.iherb.com
There have been many over the years who have posted success with Jarrow's brand there.

Their prices are much lower than locally, and they are fast in delivery and
processing your order.

There is a good alternative locally by Country Life...
It is an another activated form of B12. I have found that commonly in local stores.
example: http://www.country-life.com/moreinfo...Product_ID=191
You will pay more for this however, than the Jarrow brand.

(note-- many people use Iherb for their online shopping. We had a thread at
OBT on favorite online places at one time--- I do not have any financial
affiliation with any sales of any product mentioned here. If I direct someone it is because I have found an item of quality at a specific place that is affordable. For example for most things WalMart has
become a very complete provider. They even have the new high gamma E now. I have saved a bundle of $$ using online products. One recent example was 8oz of Inositol powder pharmaceutical grade by Jarrow for $12.95 at iherb.......locally it was $67.00! That is a huge difference but a typical example of $$ ranges ).