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Old 02-20-2007, 10:10 PM #11
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Thanks Mrs. D for the info about Hopewell. That info comes from Casewatch and is operated by the same person that operates QuackWatch, and I have absolutely no belief in anything that comes from those two sites. However, I did research Hopewell in terms of the Autism community. Many others use Hopewell successfully for MB12 shots. They are also an acceptable pharmacy on Dr. Neubrander's site and a certificate is provided for the MB12: http://www.drneubrander.com/page5.html It's not readible from my computer though. However, that's really as far as my research has gone about Hopewell. I've tried Wellness Pharmacy & College Pharmacy for MB12 shots and theirs stung like crazy which wasn't tolerable.

I had my last level of b12 check by a blood test from Spectracell Laboratories. B12 was right in reference range, but on the low border of being in it. My result was 19 and the reference range is from 15% up. That probably doesn't match the b12 serum test from Labcorp or Quest Diagnostics at all. My doctor wants me to be in the middle range of the reference range. Also some amino acid testing led to the need for more b12.

I had this same test completed over 2 years ago and interesting enough my B12 levels were the same in both. All the other nutrient levels changed over the two years. The first test 2 years ago was done before any mb12 and the 2nd test that was recently done was with mb12. So like you said it really does make me wonder.

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Old 02-21-2007, 08:00 AM #12
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Mrs D.

This is a reply that I got from Dr. Neubrander's office regarding the low B12 levels & Hopewell. What do you think of it? Also I'd be interested in giving oral B12 a try. Do you have any suggestions of B12 that doesn't contain sugar? Most of the ones I've seen contain sugar which I'm avoiding.

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Originally Posted by rlneub
B12 tests measures are not specific to what kind of B12 (methyl, cyano, hydroxy...). Raising or lowering MB12 based on B12 tests cannot be done as the test does not separate the kind of B12 you need. The only tests we use is doing the Parent Designed Report Form before making a change to the MB12 and then redoing the Form 5 weeks after a change to MB12 with NO OTHER CHANGES occurring during that 5 week period. Lastly, if you are doing B12 without the proper supplements in the proper ranges that mb12 needs to do its job, mb12 will not be utilized but excreted as excess.

Do you meet the Supplement Review Worksheet guidelines for Magnesium, Zinc, B2, B3, B6, Selenium and C? If these guidelines are low then the mb12 may not be processed and the excess goes out in the urine which may explain that the mb12 levels are similar.
http://www.autismweb.com/forum/viewtopic.php?t=9960


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Old 02-21-2007, 08:47 AM #13
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Lightbulb suggestion...

When a dosage form fails...like you are experiencing, one should consider a
change. One option is to change the pharmacy you are using, while still getting injection. The other option is to change to oral administration.

http://www.iherb.com/store/ProductDe...&pid=JRW-18004
This form of B12 is the most commonly chosen one on the forums here and at BT. This link is for the 5mg version (not all is absorbed, you know).

Taken once a day on an empty stomach for best absorption is best.

You have the right to refuse any treatment that you find ineffective or uncomfortable. Discuss this with your doctor, so you can have the blood work done before you d/c the shots, and after 3mos on the oral.

The numbers you state for B12 don't make sense. Typically they are in the "hundreds" not the "tens" but then I am not acquainted with Spectracell's ranges.
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Old 02-21-2007, 09:25 AM #14
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Thanks Mrs. D,

I'm going to discuss the oral mb12 with my doctor in a couple of weeks. I also plan on discussing his thoughts about the hunger with increased amount of mb12 dosage. I'm going to ask him about increasing the shot frequency to every other day or every day with a lower amount mb12. I don't want to switch pharmacies because I've already tried 2 others without success. I'll let you know what I decide to do.

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Old 02-21-2007, 04:28 PM #15
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Mrs. D,

I was informed that if you have yeast oral mb12 won't work because the yeast takes it all. Do you have any knowlege about this? I have yeast so I just wondered about this.

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Old 02-22-2007, 11:35 PM #16
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I wouldn't think that even an horrendous overgrowth of bacteria would be able to deplete so much.

However, maybe you have the perfect combination: severe malabsorption, serious yeast overgrowth, and ??? That sure might be part of the puzzle.

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Old 02-23-2007, 07:44 AM #17
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Question hmmmm?

If you have Candida, Carolyn I would hope you get treatment for that.
I know that parasites such as tapeworms do deplete B12.

And low b12 can simulate Candida overgrowth, but I have not seen
papers on the reverse.
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Old 02-23-2007, 01:02 PM #18
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Mrs D.

Yes, we're treating my Candida, but it's not easy to get rid of. We've been working on getting rid of it for 1 1/2 years now. I don't have parasites though, thank goodness.

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Old 02-23-2007, 02:41 PM #19
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B12 is manufactured in the GI tract by bacteria. So the candida problem means that your GI tract may not have the right bacteria or not enough of it.

I am not sure how using the sublingual form effects the absorption with candida problems.

Maybe the b12 patch would be the way to go. I think there may be a b12 cream. You might talk to your doctor about other forms besides oral and injectible.
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Old 02-23-2007, 07:41 PM #20
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It has been thought that some can manufacture some B12 in their intestines, but if it happens at all it is very little. B12 must be obtained from the outside, regardless of how efficient one is at producing the tiny bit or recycling it.

The cause of malabsorption should definitely be eliminated when possible, but this situation appears to be worse than a severe malabsorption. I would look to use or storage.

And if one is extremely rare and for some strange reason cannot get it orally with huge doses, IM shots should be the most direct way of obtaining it.

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