I'm taking methyl-b12 shots. Three months ago my doctor raised my mb12 shot dosage from 3250 mcg every three days to 5000 mcg every three days. I thought it was making me really hungry--too hungry to the point of where I constantly wanted to eat. I experimented myself and have been doing the injections every 5 days instead of every 3. The hunger went back to normal.

However, I don't notice much of a difference when doing the shots every 5 days--the difference seen was mostly improvement in bowel movements. I will be seeing my doctor in a couple of weeks and will be expressing my concern with doing the 5000 mcg every 3 days and tell him that I think I did better with 3250 mcg every 3 days. I'm hoping that he'll listen to me because being hungry all the time is a huge problem, and I won't take 5000 mcg of mb12 every 3 days if that's what occurs.

However, my question is what do I if I'm still low in b12? I've been doing
mb12 shots for 1 1/2 years and still am low in b12. For most of that time it was 3250 mcg every three days until my doctor increased it to 5000 mcg every 3 days.

Carolyn

Carolyn,

As difficult as being hungry all the time is, if it happens when you get B12, it probably is a sign of your body attempting to repair.

If you are low in B12 after all that, you store horribly. Or, if the shots were not methylcobalamin, you might have a rare inability to convert the other type to a usable form.

Are the shots definitely the methylcobalamin type?

rose

Rose,

Yes, the shots are definitely the methylcobalamin type.

Carolyn

That's exceptional! Good for you.

rose

Rose,

So are you saying that I should consider doing the shots every 3 days at 5000 mcg like my doctor had me do? That the constant hunger is a good sign?

Carolyn

Where do you obtain your injections? What company supplies it to you?
Do you get them from the doctor?

Are they compounded for you?

When a therapy fails one has to consider the drug or route of administration
is faulty, perhaps.

I once researched B12 injection. The cyano version is cleared from the serum in 72 hrs in normal people.

With your high doses, some should be in the serum, unless you are excreting it thru the kidneys at a high rate for some reason.

So I would look to the supplier of your injections. Maybe there is nothing in there? or it is subpotent?

What would happen if you subsitituted 5mg methylcobalamin ORAL daily for a while? I wonder.

Mrs. D,

I get my shots from Hopewell Pharmacy in New Jersey. They are compounded for me.

Carolyn

Yes, I am saying that it might be a good thing.

I sure would take the oral methylcobalamin. Whether the methylcobalamin shots are good or bogus, the oral is a good thing and can't hurt.

And if your symptoms have correlated (over time, not a coincidence) with the shot frequency, I would have the shots more frequently. Again, if you need that you must be an extremely rare case, but at least it is safe.

rose

You might want to read this:

http://www.casewatch.org/fdawarning/comp/hopewell.shtml

You know when you use such high doses of something often, and injected, and
you do not show blood levels that reflect that...one really has to wonder!

What was your last serum value you had tested Carolyn?

This is amazing, my Dr told me I was a little low on B12 and to start taking the pills. I have noticed I have had more of an appatite but never connected it to the B 12, wow, I'm glad I looked on this site! Thanks,