Hello I am Mavin
I have been diagnosed with Hashimotos (August 2010) and b12 Deficiency (about the first week of May 2011) In 2002 I had L-4, L-5, S-1 Fusion with stabilization bars surgery. In July of 1993 I shattered C-7 (I am lucky I walked to the car and came out of it with only some numbness in left thigh and a plate in the front)
My first b12 level was 241 after a week of daily and then once a week for four weeks then I was to go to monthly. After the second week I noticed my body not digesting food again my hair falling out again some fatigue but the burning oh man the burning! It wasnt too bad for a few more days but I called anyway to my P.A. I wanted a shot! We did levels again and I was at 307 so they are making me wait. Today for the past three days the burning and pain has taken over again! Its so bad at night. I was feeling so normal and the burning was gone! My physicians assistant care taker says they want to bring my levels up slow.
I want to make an appointment to understand what can help at home. However my understanding is that serum levels can be deceiving and IF I was to get a shot and it helps it is needed and my body just needs it on a different schedule or a slower back of off with the nerve issue if we dont stop it this will be permanent and oh man no way...
Thought? Comments? Help?

I've answered you on the other thread.

Thanks and sorry for the multiple posts. question I have made my appt to speak with care provider in the mean time I bought 5000 mcg of b12 and am taking one a day on empty stomach two day so far burning is still extreme we will see how it goes till the 8th. Is this too much on a daily basis? Or because I don't absorb from food this will be ok or????? Thoughts?

When you take it orally, only a small portion is absorbed from that 5000mcg/5mg tablet. You do not need intrinsic factor at all at this level of dose, because the B12 when given in high amounts is absorbed passively without it in the small intestine.

Shots only stay in the serum for 72 hrs. Taking orally provides the B12 in a more normal way (mimics getting from food), and then the B12 can get to more places more efficiently. The spinal cord fluid which is also in the brain, (called the CSF) takes the B12 from the serum by passive diffusion. When serum levels are low, less can get into the brain therefore. On that link I gave you is a paper from Dr. C. Snow, which explains neurological problems from "low B12". Since B12 is non-toxic and does not have negative effects, taking it in high doses is not problematic.

I raised my B12 levels to 1999 in 3 months on 5mg a day.
Many of our members at our Peripheral Neuropathy board and MS, MG boards take it this way. It is important to take on an empty stomach to facilitate the absorption, because food acts like a sponge to keep B12 away from the lining of the intestine. B12 is a very large molecule and has difficulty diffusing thru.

We are lucky that it is inexpensive and non-toxic so we can take control of providing it ourselves. So many doctors have no clue.
The medical information IS out there, doctors just don't look for it.

You should start to feel some improvement within 2 weeks. Some people feel energized, but I didn't so much. But since methyl B12 is the cofactor for melatonin synthesis in the brain, you should see improved sleeping when your levels become more normal. You will want to be high for a while over 1000 until you are better. Then you can choose to take 1000mcg/1mg daily thereafter. The liver stores B12 for the future, so each dose is providing that as well...takes a while to accumulate.

You might consider having SpectraCell nutritional blood analysis performed, as it looks at the levels inside one's cells. Some people have genetic variations which may hinder the transfer of the desired nutrients into the cells themselves. For instance, on can have the MTHFR polymorphism, or a vitamin D cell-receptor polymorphism.