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Old 03-15-2012, 07:42 AM #1
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I am a ulcerative colitis patient with a serious migraine issue. The only thing that helps as an abortive is a NSAID like Ibuprofen, Neproxen etc. But they lead to GI discomfort that mimics ulcerative colitis flare and I end up with Prednisone course.
Ok, you didn't ask this, but I'm going to mention it anyway, FWIW. I have crohn's/IBS & can't tolerate NSAIDs either. As little as 2 aspirin or 1 ibuprofen will cause bleeding, though not so bad as yours requiring pred.

I've found I can tolerate meloxicam, a prescrip NSAID, on occasion. My doc recommended it as it's much gentler on the system than most others in that class.

I just can't see someone going through a course of pred over a migraine (and I get those several times a month).

Doc
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Old 03-15-2012, 09:26 AM #2
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Ok, you didn't ask this, but I'm going to mention it anyway, FWIW. I have crohn's/IBS & can't tolerate NSAIDs either. As little as 2 aspirin or 1 ibuprofen will cause bleeding, though not so bad as yours requiring pred.

I've found I can tolerate meloxicam, a prescrip NSAID, on occasion. My doc recommended it as it's much gentler on the system than most others in that class.

I just can't see someone going through a course of pred over a migraine (and I get those several times a month).

Doc
OK, I will break my rule too
I start bleeding in less than 2 hours of taking Ibuprofen or Neproxen. I am currently using Nabumetone 750mg but it isn't as good as Ibuprofen or Neproxen. My neuro wanted me to give a try to Celebrex but I can't afford it so Nabumetone instead. Gave Dolgic Plus a try, useless.
I will ask for Meloxicam Rx. I wonder what is your dose and the indication?


Plus, I have to mention something that I should have said in the first post.
Last year, I had kidney stone. Now I am not too sure if it was because of ulcerative colitis or Topamax 125mg that I was taking about 8 months prior to that. Magnesium seems to be watched for folks with kidney issues. I don't know how in my case, so if anyone has any experience on it, a comment is welcome.
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Old 03-15-2012, 10:21 AM #3
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Anyone with kidney disease should discuss magnesium use safety with their doctor.

For someone with colitis, it might be easier to use a topical form of magnesium, since magnesium is often stimulating to bowel function and transit. People differ in their reactions to magnesium oral, so you'll just have to try and see if it works without causing further diarrhea.

You can get magnesium from certain foods, and that is also gentler than oral supplements.
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Old 03-15-2012, 12:21 PM #4
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@ mrsD,

With your previous post, there are actually quite many links that are dead, its almost 24 pages thread and I didn't keep a track of dead links. Sorry.

With topical Mg, I am considering Epson salt baths but the issue there is, you don't know how much Mg is getting absorbed and if I have to use it for my migraine purpose, I need a daily regimen. May be I will not use citrate or similar forms and stick to gluconate form and slow release chloride form. But before I make any decision and talk to my neuro, I wanted to see the consensus here.

With food sources, I have already included many, still they are not good for a daily regimen.
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Old 03-15-2012, 12:31 PM #5
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I will ask for Meloxicam Rx. I wonder what is your dose and the indication?
I take meloxicam (15 mg/day - the max dosage) for arthritis/joint pain, when it's just too much too handle. It works quickly - within an hour; better with a potentiator like acetaminophen.

I don't get an aura or indication/warning for migraine - it just starts, but the faster/stronger I can hit it, the quicker/easier it goes away. Sitting still those first 2 hours is mandatory or I may as well take a placebo. Myofascial massage helps too, especially with the bad ones that make me nauseous and perspire profusely. Promethazine (an antihistsmine/potentiator) can help too. I've used maxalt as an abortive for years (none of the prophylactics worked, but I found other treatments like PT, myofascial trigger point massage, traction...) but I can no longer afford the maxalt, so I'm looking first for another (generic) triptan. If that doesn't work, I'm not sure - I'll have to keep digging into migraine treatment sites.

Topamax is very likely (IMO) a culprit for kidney stones; that was one of the reasons I refused it (along with more homework). When the neurologist first gave me the sample & scrip (only migraine sample I've ever gotten that came with a month's supply), it was accompanied by an 8-1/2 x 11 sheet warning about kidney stones with the medication. That was a first too.

I did try magnesium lactate after searching: best absorbed magnesium, and there were admonitions about folks with kidney complications taking any magnesium supplements, recommending intravenous (if deficient) or topicals like epsom salts.

Doc
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Old 03-15-2012, 01:16 PM #6
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I did try magnesium lactate after searching: best absorbed magnesium, and there were admonitions about folks with kidney complications taking any magnesium supplements, recommending intravenous (if deficient) or topicals like epsom salts.

Doc
Thank you for all information on migraine.

With Mg lactate supplement, could you please tell me the brand you used? Did you see any effect?
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Old 03-15-2012, 01:45 PM #7
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Thank you for all information on migraine.

With Mg lactate supplement, could you please tell me the brand you used? Did you see any effect?
I'm sorry, I do not recall the brand; it was whatever well-known brand that we got the best deal on at the time we ordered. We've found the whole supplement industry to be so competitive that rechecking every month/order has been worth the time/effort. Once we find a good deal, we sometimes get a better one by auto-re-ordering.

Unfortunately, I saw no effect, and discontinued after about 6 months, but I would not discourage anyone from trying it based on my results.

Doc
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