[Ziggy7]

So I got some test results back today and amongst a host of other things, I noticed my cortisol/dhea 12h test was wildly abnormal with DHEA being consistently low throughout the day and cortisol being very low except for once at midnight when it suddenly increased over the norm. The results note this pattern indicates a problem with the hypothalamic pituitary axis. I should probably note my melatonin came back insanely high (!) at 100 with a normal range of 1-5.

I have forwarded the results to my immunologist, but I'm just wondering if there's something that might help the adrenals (or the hypothalamic pituitary axis) or melatonin from a herbal/vitamin/supplement perspective?

Ziggy

[Dr. Smith]

Originally Posted by Ziggy7

I'm just wondering if there's something that might help the adrenals (or the hypothalamic pituitary axis) or melatonin from a herbal/vitamin/supplement perspective?

I don't know about the melatonin. The adrenals can be addressed, but I wouldn't mess with them without your doctor's involvement.

I'm doing it with my doctor's involvement:
http://neurotalk.psychcentral.com/thread156416.html

Doc

[mrsD]

Have you had a brain MRI? strange things (cysts or adenomas) with hormones may show up either in the pituitary/hypothalamus area or pineal gland (melatonin).

There are benign adenomas that occur in the pituitary from some drugs...mainly the atypical antipsychotics.

But with age many people get low in DHEA...this is fairly common.
There is also a connection with the thyroid, so adjusting one without the other consideration is important and needs an experienced doctor.

[Ziggy7]

Hi Doc and thanks for the reply! I'll look at your thread and of course get my doc's advice...! Hope your treatment's working for you!

Hello Mrs D and thank you for the reply!

The last time I had a brain MRI was three years ago and there was no cyst/adenomas in sight, but I guess some time has passed... I've never taken atypical antipsychotics (or typical antipsychotics for that matter), but it's interesting to know drugs can affect adenomas....

Actually the bizarre thing is last year my cortisol and DHEA were fine (cortisol was a little on the low side, but nothing like this). I'm 26 years old btw; would DHEA be low at that age?

Thyroid! Aha! Thyroid tests aren't back yet! I should get them back tomorrow and I will investigate!!

Ziggy

[mrsD]

No, not common at your age. So do get it looked at.

There are some suggestions that Vitamin B5 (pantothenic acid) helps adrenal functions.

Here is monograph on it:

http://lpi.oregonstate.edu/infocenter/vitamins/pa/

It is not common to be low in this nutrient, but with your history of malabsorption, it might be important for you.

[Dr. Smith]

Originally Posted by Ziggy7

Hi Doc and thanks for the reply! I'll look at your thread and of course get my doc's advice...! Hope your treatment's working for you!

It IS, and thanks. It's not a panacea; there's no such thing, but it is a cuss of an improvement in several areas.

Doc

[Marlene]

In addition to B5, vitamin C is important for proper adrenal function. I use a buffered acsorbic acid, about 1000mg /day. You can start of with 500 mg/day and increase it over time. 500 mg/ 3x/ day.

[Dr. Smith]

Originally Posted by Marlene

In addition to B5, vitamin C is important for proper adrenal function.

I don't recall offhand if I knew that or not, as I've been taking 500 mg. of vitamin C for years anyway. My stomach/system can't handle ascorbic acid so I use Ester C (which may be what you mean by "buffered"), which is allegedly (but disputably) better absorbed/assimilated/bioavailable. I'll keep using it anyway just due to the former reason.

Doc

[Marlene]

I don't think it's the same. I too cannot tolerate the pure/plain acsorbic acid. I do use the buffered form and seem to do well with it. I try to take 1000 to 1500 a day.

[Dr. Smith]

Originally Posted by Marlene

I don't think it's the same. I too cannot tolerate the pure/plain acsorbic acid. I do use the buffered form and seem to do well with it. I try to take 1000 to 1500 a day.

It is confusing, but I agree. If you google: is ester c buffered you'll find all kinds of combinations using the word "buffered", which IMO, is poorly defined. Ester C is patented, and as such, has a very specific formula/process involved in its manufacture. "Buffered" could mean almost anything, which could apply to Ester C or to some other formula/additives.

What's important for any of the forms of vitamin C is, is it working for you and doing what it's supposed to do.

Doc