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Vitamins, Nutrients, Herbs and Supplements For discussion about vitamins, vitamin deficiency, herbal remedies and other supplements. |
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01-23-2009, 08:24 PM | #1 | |||
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came upon some information and didn't really understand what it meant?:
coenzyme Q10 shares a common biosynthetic pathway with cholesterol. The synthesis of an intermediary precursor of Coenzyme Q10, mevalonate, is inhibited by some beta blockers, blood pressure-lowering medication,[20] and statins, a class of cholesterol-lowering drugs.[21] Statins can reduce serum levels of coenzyme Q10 by up to 40%.[22] Some research suggests the logical option of supplementation with coenzyme Q10 as a routine adjunct to any treatment that may reduce endogenous production of coenzyme Q10, based on a balance of likely benefit against very small risk. does this mean that coq10 affects efficacy of beta blockers, or beta blockers affects absorption of coq10?
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dx: fatigue,, SOB at times(asthma), insomnia, anxiety. fatigue, insomnia, migraine issues neurontin omega 3 fish oil, b complex, acid blocker(famotidine) Lopressor NAC low dose aspirin Former, experience in: Prozac |
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01-23-2009, 08:29 PM | #2 | |||
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Wisest Elder Ever
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Quote:
Their effect is much less than the statins. CoQ-10 does not affect beta blockers that I know of. CoQ-10 is involved in the functions of the mitochondria in the cells of muscles. These cells provide energy for muscle contraction. Low levels of CoQ-10 may cause heart failure over time.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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"Thanks for this!" says: | bruegger84 (02-04-2009), judymoody (01-23-2009) |
01-23-2009, 09:05 PM | #3 | ||
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I don't want to hijack your post Bruegger, but I have a question about this as well, and you all have the experience and knowledge . . . does CoQ10 need to be taken in conjunction with Acetyl Carnitine, Vit C. and a food source containing fats in order for best absorption? I, too, am trying to discover how best to use supplements . . . and what works for me.
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01-23-2009, 11:23 PM | #4 | ||
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My Daughter takes COQ10 for her ME and has found it to be very beneficial.
She says that you do need a bit of fat with the meal when you take the COQ10. She also says that you must use the Ubiquinol version, not the Ubiquinone one.
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See my mosaics . . Last edited by Peter B; 01-24-2009 at 07:50 AM. Reason: added more detail |
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"Thanks for this!" says: | judymoody (01-24-2009) |
01-24-2009, 04:30 PM | #5 | |||
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I assumed jarrow would contain the most absorbable one, but they don't they use ubiquinone, but they market it under q-absorb, supposedly a higher absorbability version.
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dx: fatigue,, SOB at times(asthma), insomnia, anxiety. fatigue, insomnia, migraine issues neurontin omega 3 fish oil, b complex, acid blocker(famotidine) Lopressor NAC low dose aspirin Former, experience in: Prozac |
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01-24-2009, 04:52 PM | #6 | |||
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Wisest Elder Ever
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The ubiquinol version mentioned by PeterB is a new form.
It is "activated" and much less/milligram is needed. It also costs much more money. For someone critically in need, the specs are different than for others.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei ************************************ . Weezie looking at petunias 8.25.2017 **************************** These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.
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01-24-2009, 05:12 PM | #7 | ||
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I beg to differ that the Ubiquinol version is "necessary". Better, perhaps, but not necessarily, necessary A family member with severe, complex pediatric-onset migraines (often associated with need for CoQ10) was put on a very absorbable ubiquinone from www.lef.org -- and it worked extremely well.
The family looked into ubiquinol after it hit the market, but failing to find a brand without soy, which the person is allergic to (there may now be one... anyone know of a brand without soy?), and seeing that what the person was on worked, just kept her on the "super absorbable ubiquinone." |
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"Thanks for this!" says: | bruegger84 (02-04-2009), Vowel Lady (01-26-2009) |
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