Vitamins, Nutrients, Herbs and Supplements For discussion about vitamins, vitamin deficiency, herbal remedies and other supplements.


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Old 11-28-2006, 03:17 PM #1
jccgf jccgf is offline
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jccgf jccgf is offline
Senior Member (jccglutenfree)
 
Join Date: Aug 2006
Location: Wisconsin
Posts: 1,581
15 yr Member
Default Oral B12 saves cost....

Duh! So, maybe NOW our doctors will "hear" that oral B12 works?

Comparing costs of intramuscular and oral vitamin B12 administration in primary care: A cost-minimization analysis. 2006

Quote:
Objective: To establish whether savings could be made by changing patients from intramuscular to high doses of oral vitamin B12 in primary care without compromising their wellbeing. Methods: Cost-minimization analysis from a UK perspective, using secondary data obtained from the literature available and expert opinion. Results: The cost of the resources used to treat patients with vitamin B12 deficiency with intramuscular vitamin B12 was calculated as between pound55.99 (euro83.1) and pound99.99 (euro148.5) per year. The cost of treating patients with high doses of oral vitamin B12 during the first year was between pound125.55 (euro186.5) and pound248.55 (euro369.1). However, once patients receiving intramuscular treatment had been converted to oral treatment, or in new patients treated orally from the outset, the cost was pound35.55 per year (euro52.8). One variable, home visits, had a high impact on the calculations.Conclusion: Switching patients with vitamin B12 deficiency from intramuscular to high-dose oral therapy and treating patients newly diagnosed with vitamin B12 deficiency with oral vitamin B12 from the outset could save resources in the medium and long term, and in newly diagnosed patients. Savings would come particularly in the form of nursing time.
PMID: 17127603
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Old 11-28-2006, 03:22 PM #2
jccgf jccgf is offline
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jccgf jccgf is offline
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Default Copper Deficiency resembles B12 deficiency

Copper Deficiency Myeloneuropathy Resembling B12 Deficiency: Partial Resolution of MR Imaging Findings with Copper Supplementation.
PMID: 17110677 Nov 2006

Quote:
SUMMARY: Copper deficiency has been associated with a clinical syndrome, myeloneuropathy. Radiographic changes resembling B(12) deficiency in the cervical spinal cord have been described. We present a case of copper deficiency myeloneuropathy, with cervical MR imaging findings resembling B(12) deficiency, which partially reversed following copper supplementation. This is, to our knowledge, the first described case of radiographic improvement with copper supplementation.
PMID: 17110677
Copper deficiency myelopathy (human swayback).
PMID: 17036563 Oct 2006

Quote:
The hematologic manifestations of copper deficiency are well known and include anemia and neutropenia. In the past few years, the neurological manifestations of acquired copper deficiency in humans has been recognized, the most common being a myelopathy presenting with a spastic gait and prominent sensory ataxia. The known causes of acquired copper deficiency include prior gastric surgery, excessive zinc ingestion, and malabsorption; however, often the cause is unclear. Hyperzincemia may be present even in the absence of exogenous zinc ingestion. The clinical features and neuroimaging findings are similar to the subacute combined degeneration seen in patients with vitamin B12 deficiency. Copper and vitamin B12 deficiency may coexist. The neurological syndrome may be present without the hematologic manifestations. Copper supplementation resolves the anemia and neutropenia promptly and completely and may prevent the neurological deterioration. Improvement, when it occurs, is often subjective and preferentially involves sensory symptoms. This article describes patients with copper deficiency myelopathy seen at the Mayo Clinic in Rochester, Minn, and reviews the literature on neurological manifestations of acquired copper deficiency in humans.
PMID: 17036563
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Last edited by jccgf; 11-28-2006 at 03:28 PM.
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Old 11-28-2006, 03:25 PM #3
jccgf jccgf is offline
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jccgf jccgf is offline
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Join Date: Aug 2006
Location: Wisconsin
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Default More on B12

Diagnosis and treatment of vitamin B12 deficiency--an update.
PMID: 17043022 Nov 2006

Quote:
We represent an update on diagnosing and treatment of vitamin B12 deficiency. Vitamin B12 deficiency should be suspected in all patients with unexplained anaemia and/or neurological symptoms,as well as in patients at risk of developing vitamin B12 deficiency such as the elderly and patients with intestinal diseases. Measurement of plasma cobalamins is suggested as the primary analysis followed by measurement of plasma methylmalonic acid in unsettled cases. Accumulating evidence indicates that the biologically active cobalamin,plasma holotranscobalamin (holoTC),may be superior to plasma cobalamins, and measurement of holoTC is currently introduced in the clinical setting. No consensus exists concerning evaluation of the cause for vitamin B12 deficiency,and pros and cons on the different tests mainly aiming at evaluation of the function of the gastric mucosa are presented. Once the diagnosis of vitamin B12 deficiency has been confirmed efficient treatment can be ensured either by injections every 2-3 month or by a daily dose of 1 mg vitamin B12.
PMID: 17043022
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