I'm on Methyl-B12 shots and have been for almost 1 1/2 years. However, back in August my doctor increased my shots dosage. I had been injecting
3250 mcg of methy-b12 every 3 days. He increased it to 5000 mcg every 3 days.

I know Methyl-B12 is said to make you hungry. However, I'm wondering if too much Methyl-B12 could make you hungry constantly. Has anyone experienced this with Methyl-B12 or know if that's possible?

My appetite has increased so much since this increase in Methyl-B12, and I'm not liking it one bit. I don't know if it's linked to this increase in Methyl-B12 or not, but I'm also having horrible cravings.

Carolyn

I had a similiar problem when my histamine levels became balanced. I continued taking my supplements as I had been and that caused me to have HIGH histamine levels (I had finished the loading phase, which caused my low histamine levels to become high). One problem was that my appetite was through the roof. I wanted to eat all the time. The solution for me was to lower my dose of niacin. That returned my appetite to what it had been before.

B12 also plays a role in methylation, and it relates to histamine levels. B12 can raise histamine levels. High histamine types are known for having a hearty appetite. (I was also eating too much sugary foods when my histamine levels were on the high side.)

I think you should talk to your doctor about the dose being too high. That would be the first choice. I think you may be done with the loading phase of the b12 supplementation, which means your tissues are saturated with b12 now. You should supplement b12 but at a lower dose now.

If you feel your appetite is not healthy, but basically out of your control, then it might indicate that the dose is too high. My appetite was not healthy but I had these cravings (for sugary foods) that I would only get when I had a yeast overgrowth. I know my appetite was not normal or healthy, but that is something you need to discuss with your doctor. (A yeast problem would cause an increase in appetite for ONLY sugary or starchy foods.)

I searched around for you a bit today, and could only find some vague
references to "improving" appetite with B12 (when one is run down and
deficient).

You know, historically B12 was used commonly in the "old" days when
patients complained of feeling fatigued. Doctors routinely gave B12 shots,
and I recall getting some in the '70's. Back then not much was known
medically about many things so doctors did what they thought might work.
This resulted in a controversy, that giving B12 willy-nilly was quack medicine.
This backlash persists to this day and the overreaction to ignore B12 completely is just as bad or worse.

So I think you should discuss this with your doctor. Why he thinks you need
such high doses. And if he gives you some good reasons, with some studies/references perhaps, you could share them here with us?

The extensive reading I have done has revealed no such thing as "too much B12," especially methylcobalamin.

Since the results of deficiency are so diverse, the answers are likewise diverse. Type of damage, extent of damage, etc. And there is a multitude of temporary (not necessarily short term) effects that may pass as repairs are made.

I would keep up the B12 and make as sure as possible that other nutrients are there in sufficient quantities.

rose