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Well, the only proven supplement to lower C-reactive protein is Vitamin C.

Quote:

Free Radic Biol Med. 2009 Jan 1;46(1):70-7. Epub 2008 Oct 10.Click here to read Links
Vitamin C treatment reduces elevated C-reactive protein.
Block G, Jensen CD, Dalvi TB, Norkus EP, Hudes M, Crawford PB, Holland N, Fung EB, Schumacher L, Harmatz P.

University of California, Berkeley, 94720, USA. gblock@berkeley.edu

Plasma C-reactive protein (CRP) is an inflammatory biomarker that predicts cardiovascular disease. Lowering elevated CRP with statins has reduced the incidence of cardiovascular disease. We investigated whether vitamin C or E could reduce CRP. Healthy nonsmokers (N=396) were randomized to three groups, 1000 mg/day vitamin C, 800 IU/day vitamin E, or placebo, for 2 months. Median baseline CRP was low, 0.85 mg/L. No treatment effect was seen when all participants were included. However, a significant interaction was found, indicating that treatment effect depends on baseline CRP concentration. Among participants with CRP indicative of elevated cardiovascular risk (> or =1.0 mg/L), vitamin C reduced the median CRP by 25.3% vs placebo (p=0.02) (median reduction in the vitamin C group, 0.25 mg/L, 16.7%). These effects are similar to those of statins. The vitamin E effect was not significant. In summary, treatment with vitamin C but not vitamin E significantly reduced CRP among individuals with CRP > or =1.0 mg/L. Among the obese, 75% had CRP > or =1.0 mg/L. Research is needed to determine whether reducing this inflammatory biomarker with vitamin C could reduce diseases associated with obesity. But research on clinical benefits of antioxidants should limit participants to persons with elevations in the target biomarkers.

PMID: 18952164 [PubMed - in process]

PMCID: PMC2631578 [Available on 2010/01/01]

Fish oil is one of the best agents to raise HDL.
It also reduces blood clotting but that is a small effect.

Lovasa RX is a fish oil designed for cardiovascular effects.
But you can get it less expensively OTC generically at Costco or SAMs now.
The triple strength caps are close to Lovasa in dose.

Mrs. D.
That's a good study.
Thanks.
M.

Vitamin D- absorbability

Once again, many thanks for your diligence in keeping the rest of educated and healthier of course! but yet - another question- is Vit. D better absorbed in a stand alone gelcap, or is absorbency enhanced in a supplement like Jarrow's Bone-Up, or does it matter?? Julie

I take a gelcap...it is mixed in an oil. I really don't think the dry powder type supplement is a good idea for D, since it is oil soluble.

I use a supplement enhancer for my morning supps. It is called Bioperine, made by Source Naturals.
Here is a thread about it at PN
http://neurotalk.psychcentral.com/sh...ight=bioperine

I became interested in it because of the Doctor's Best products which have it added. Also there was a study showing this pepper extract can lower cholesterol! So I've been using it.

One has to be careful with DRUGS and Bioperine. Not much information is available on the net about the drugs which may be affected by it. But until further info comes along I think it is similar to the effects of grapefruit juice on drug levels.

I am not really recommending Bioperine for others at this time because of this unknown factor. But I don't take any drugs in the morning, so I am using it to enhance my supplements.

New article on Vit D....children

http://news.yahoo.com/s/ap/20091026/...vitamin_d_kids

Quote:

Using the American Academy of Pediatrics' cutoff for healthy vitamin D levels, 6.4 million children — about 20 percent of kids that age — have blood levels that are too low. Applying a less strict, higher cutoff, two-thirds of children that age, including 90 percent of black kids and 80 percent of Hispanics, are deficient in vitamin D.

A Pediatrics editorial says the strongest evidence about effects of vitamin D deficiency in kids involves rickets, a bone disease common a century ago but that continues to occur.

Rickets can be treated and prevented with 400 units daily of vitamin D, the editorial says. The pediatricians' group recently recommended that amount for all children, saying that most need vitamin supplements......
Exactly how much vitamin D children and adults should get, and defining when they are deficient, is under debate. Doctors use different definitions, and many are waiting for guidance expected in an Institute of Medicine report on vitamin D due next year. The institute is a government advisory group that sets dietary standards

While the statistics are revealing....the dosing is not great.
This demostrates that physicians will test, but don't want to treat this aggressively enough.

Here is an article that discusses the big question:

How much should I take?

http://www.naturalnews.com/027345_Vi...ure_blood.html

Vit D and metabolic syndrome:

This is a very interesting link:

http://people.csail.mit.edu/seneff/o...amin_D_Obesity

Thanks to pabb for sharing it!

Cholesterol and Vit D:

Here's another interesting link for all of us Vit D users...thanks Mrs. D for all your info.

http://www.medicalnewstoday.com/articles/177447.php

New study on Vit D...shows no cancer prevention for some types:

http://news.yahoo.com/s/hsn/20100619...ucescancerrisk

This study was done for only certain types of cancer (not all of them).

And one link was found to higher rates of pancreatic cancer for those with higher blood levels of D. More work is needed to explain that result, as there may be certain variables for those people in addition to the D levels.