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Weight Loss & Healthy Living For weight loss and healthy living discussions. |
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03-11-2016, 06:47 AM | #1 | |||
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Grand Magnate
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This article may be of interest to the NT community; http://www.sciencemag.org/news/2016/...&et_cid=332196
An explanatory comment; "good cholesterol" (HDL) is generally protective against cardiovascular disease because it delivers excess cholesterol to the liver (a process called reverse cholesterol transport) - the liver then disposes of it. SR-BI (referred to in the link) is a scavenger receptor, expressed on liver cells - its job is to allow HDL to dock to those cells, allowing them to take up cholesterol and dispose of it. If SR-BI is absent or defective, this process does not work well.
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03-11-2016, 07:19 AM | #2 | |||
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Wisest Elder Ever
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Pfizer had a plan to put their HDL drug which was in trials added to Lipitor. But some people in that study died, so they scrapped it.
More here: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1702474/
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