There is a moderate drug interaction with tramadol and zofran.
http://www.drugs.com/interactions-ch...21-0,1752-1120
Tramadol has to be activated by the liver to its active metabolite in order to work. So there can be a delay of up to hours before you have pain relief. So people often increase dosing...before that can happen, and then they end up with significant side effects.
I for example, cannot tolerate tramadol in high doses...causes terrific nausea for me. So I only use 25mg (1/2 of a 50mg tablet). And even then I reserve it for really bad nights only.
__________________
All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
************************************
.
Weezie looking at petunias 8.25.2017
****************************
These forums are for mutual support and information sharing only. The forums are not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider. Always consult your doctor before trying anything you read here.