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04-12-2014, 01:23 PM
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#7 | |||
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Wisest Elder Ever
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There is a moderate drug interaction with tramadol and zofran.
http://www.drugs.com/interactions-ch...21-0,1752-1120 Tramadol has to be activated by the liver to its active metabolite in order to work. So there can be a delay of up to hours before you have pain relief. So people often increase dosing...before that can happen, and then they end up with significant side effects. I for example, cannot tolerate tramadol in high doses...causes terrific nausea for me. So I only use 25mg (1/2 of a 50mg tablet). And even then I reserve it for really bad nights only.
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