I have taken Inosine for a short time. Not sure of the results at this point. I have no issue with supplements at all.

I think they are essential. Not everything is technically a supplement though. When compared to things like anti-seizure meds, opiods and narcotics I think there really is no reason to have any fear.

I have felt some temporary relief with B-12 in high dosage as well as R-Lipoic acid. Problem with R-Lipoic is if I take to much i lose too much weight. So i have to cycle it on and off. Chromium and Inositol are great at keeping blood sugar levels at a modest level.

The key thing is to understand that supplements also have side effects, so you have to stay on top of your dosages and the occurrence of any unusual symptoms. Also, seek out reputable supplement providers. there are ones out there that are not potent or have questionable sources.