Thank you for this. Basically, I asked because an older friend is on them and has been for months because he is leaking protein. I don't know how long he wants to be on them. The other option, if it gets worse is chemo.
Quote:
Originally Posted by mrsD
There is a paper showing a reduced rate of ACE side effects, with Atacand (which is an ARB, ACE receptor blocker).
http://www.ncbi.nlm.nih.gov/pubmed/12222554
So people who react strongly to elevated bradykinin need to be vigilant if this drug is used after a reaction to ACE inhibitors.
This article is interesting too:
http://www.jneurosci.org/content/25/35/7986.full
The ACE drugs are derived from snake venom. They have a wide range of effects on tissue. Mostly swelling, fluid retention, and lowered blood pressure and increased pain due to NMDA receptor activity.
This link shows the chemical cascade of elevated bradykinin:
ttps://www.firazyr.com/hcp/about-hereditary-angioedema/bradykinin |