Thread: Tysabri Information and Check In part 2
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Old 02-24-2010, 12:18 AM
Harry Z Harry Z is offline
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Join Date: Sep 2006
Location: London, Canada
Posts: 241
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Harry Z Harry Z is offline
Member
 
Join Date: Sep 2006
Location: London, Canada
Posts: 241
15 yr Member
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Quote:
Originally Posted by komokazi View Post
The explanation still makes no sense to me. The summary to me states that cellular immune response to viruses is increased in the blood which makes sense given Tysabri's mechanism of action of confining antibodies to the bloodstream.

Obviously the problem with PML is that the virus is out of the bloodstream and into the CNS and Tysabri keeps antibodies out of the CNS.
I guess the question remains is do you really want viruses (not just JCV) proliferating in your bloodstream which Tysabri seems to allow. Maybe some very scientific person will see this and comment.

Harry
Harry Z is offline