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Originally Posted by Harry Z
This is what I got back and it kind of makes sense to me.
Harry
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The explanation still makes no sense to me. The summary to me states that cellular immune response to viruses is increased in the blood which makes sense given Tysabri's mechanism of action of confining antibodies to the bloodstream.
Obviously the problem with PML is that the virus is out of the bloodstream and into the CNS and Tysabri keeps antibodies out of the CNS.