I too have been injecting myself, in my case with Interferon for Polycythemia Vera. I inject only into the belly and have no pain, not ANY pain (well, a faint sting). However, the INF is giving me very bad neuropathy in my feet. about 10 hours after the shot, three times a week, the blow torch on my toes starts and goes on for hours. Demerol has not been enough to stop it in the moderate dose I consider OK, so I am taking Tylenol, which is a risk because I have Porphyria too. This is awful. Worst misery of my life, I think, but of course we do forget the horrors we went through, like the neurological impairments I had leading up to MS diagnosis. But for sheer pain, this is as
bad as Shingles, and harder to mollify. I am thinking I may not continue.