Jan, you are going to want to start slowly with the R-lipoic.
Perhaps take it every other day for a week or so, until you think you can handle it daily. (this would be the 100mg) and take it in the morning.
It may lower blood sugars, and if you have palpitations, it might aggravate that also. I started at 50mg a day... back when.
And I cannot really tolerate more than 100mg a day now.
A couple of posters here have had the same experience, but the majority don't seem to have a problem with it at all.
So just go slowly in the beginning.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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