FWIW, I tried going from 100 mg to 200 mg. I experienced no problems whatsoever, but there were no appreciable benefits by raising the dose either, so on that basis (and additional cost) I dropped back down to 100 mg without incident. In my mind this just supports that:
1. Everyone's sensitivity/response to RLA is different, and
2. More isn't necessarily better.

I do wish it worked for everyone as well (and as quickly) as it has worked for me; IMO it was the turning point.

I have since experienced additional benefit when I added pantothenic acid (B5), verified by stopping & starting it again. What I get from this is, if the RLA doesn't seem to help any, I'd try adding B5 before abandoning it altogether (I don't know of any evidence that B5 alone would help unless one were deficient in it, which would be possible, but unlikely/rare).

Best wishes,

Doc