It doesn't really matter much with supplements. Once you saturate your system, I think a skip here and there doesn't do much harm.
There is a similar tolerance to drugs too. Blood pressure drugs, and nitrates (for angina) have a tolerance where the body gets "used to" them and they stop working.
HCTZ you are taking depletes these nutrients:
sodium
potassium
magnesium
phosphorus
zinc
CoQ-10
This according to the Drug Induced Nutrient Depletion Handbook, 2nd ed.
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All truths are easy to understand once they are discovered; the point is to discover them.-- Galileo Galilei
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Weezie looking at petunias 8.25.2017
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