ALS For support and discussion of Amyotrophic lateral sclerosis (ALS), also referred to as "Lou Gehrig's Disease." In memory of BobbyB.


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Old 09-16-2014, 06:46 PM #1
anon1028 anon1028 is offline
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Join Date: May 2013
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anon1028 anon1028 is offline
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Join Date: May 2013
Posts: 1,229
10 yr Member
Default Good research article

i'm from the brain injury room but saw this in article and figured I'd post it,, You guys probably know about it already.

http://www.nytimes.com/2014/09/16/sc...e=article&_r=0


Kevin Eggan, also with the Harvard Stem Cell Institute, uses the technique to study amyotrophic lateral sclerosis, or Lou Gehrig’s disease. Five years ago, he took skin cells from two women sick from the same genetic form of A.L.S. He turned these skin cells into stem cells and then into nerve cells, and noticed an electrical problem: The cells weren’t signaling to one another properly, which was probably causing the neural degeneration that characterizes A.L.S.

He replicated these nerve cells thousands of times and then tested thousands of drug compounds to see which would correct the electrical signaling problem. He found a candidate drug — an existing medication approved for epilepsy — that will be tested in A.L.S. patients as soon as the end of this year.
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